Przejdź do zawartości
Merck
Wszystkie zdjęcia(2)

Key Documents

Inne dokumenty

SMB00314

Sigma-Aldrich

Coptisine Chloride

≥98% (HPLC)

Synonim(y):

Coptisine chloride, Bis(methylenedioxy)protoberberine chloride, Coptisin Chloride

Zaloguj sięWyświetlanie cen organizacyjnych i kontraktowych
Wszystkie zdjęcia(2)

About This Item

Wzór empiryczny (zapis Hilla):
C19H14ClNO4
Numer CAS:
6020-18-4
Masa cząsteczkowa:
355.77
Numer MDL:
MFCD00016676
Kod UNSPSC:
12352205
Identyfikator substancji w PubChem:
329824946

Poziom jakości

200

Próba

≥98% (HPLC)

Postać

powder

Zastosowanie

metabolomics
vitamins, nutraceuticals, and natural products

temp. przechowywania

−20°C

ciąg SMILES

C1(OCO2)=C2C=C(CC[N+]3=C4C=C5C(C(OCO6)=C6C=C5)=C3)C4=C1.[Cl-]

InChI

1S/C19H14NO4.ClH/c1-2-16-19(24-10-21-16)14-8-20-4-3-12-6-17-18(23-9-22-17)7-13(12)15(20)5-11(1)14;/h1-2,5-8H,3-4,9-10H2;1H/q+1;/p-1

Klucz InChI

LUXPUVKJHVUJAV-UHFFFAOYSA-M

Powiązane kategorie

Opis ogólny

Coptisine chloride is a cytotoxic isoquinoline alkaloid. It is the major bioactive compound of Coptis rhizome, and can also be found in different plants such as Chelidonium majus, Enantia chlorantha. Coptisine is related to berberine and has a similar structure to that of Jatrorrhizine.

Zastosowanie

Coptisine Chloride has been used to study its binding interactions with single-stranded poly(A) using different absorbance and thermal melting spectroscopic experiments. It may have been used as a standard to analyze Chelidonium majus L. extracted compounds using UV/VIS absorption spectroscopy.

Działania biochem./fizjol.

Coptisine Chloride is a potent anti-malarial compound, which also exerts anti-cancer and anti-diabetic properties. It elicits protective effects on gastric mucus membrane and is used as a traditional medicine against gastroenteric diseases. Coptisine chloride also displays anti-microbial activities.It has been analyzed as a cytotoxic agent in hepatoma and leukemic cells and is reported to block cell cycle progression.
This page may contain text that has been machine translated.

Piktogramy

Skull and crossbones
GHS06

Hasło ostrzegawcze

Danger

Zwroty wskazujące rodzaj zagrożenia

H300 + H330

Zwroty wskazujące środki ostrożności

P260 - P264 - P271 - P284 - P304 + P340 + P310 - P403 + P233

Klasyfikacja zagrożeń

Acute Tox. 2 Inhalation - Acute Tox. 2 Oral

Kod klasy składowania

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

Klasa zagrożenia wodnego (WGK)

WGK 3

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

Certyfikaty analizy (CoA)

Poszukaj Certyfikaty analizy (CoA), wpisując numer partii/serii produktów. Numery serii i partii można znaleźć na etykiecie produktu po słowach „seria” lub „partia”.

Masz już ten produkt?

Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Klienci oglądali również te produkty

Slide 1 of 4

1 of 4

Berberine chloride form

Sigma-Aldrich

B3251

Berberine chloride form

Finasteride ≥98% (HPLC), powder

Sigma-Aldrich

F1293

Finasteride

Acrylamide suitable for electrophoresis, ≥99%

Sigma-Aldrich

A8887

Acrylamide

Prednisolone ≥99%

Sigma-Aldrich

P6004

Prednisolone

Awet Alem Teklemichael et al.
Malaria journal, 19(1), 204-204 (2020-06-10)
Herbal medicine has been a rich source of new drugs exemplified by quinine and artemisinin. In this study, a variety of Japanese traditional herbal medicine ('Kampo') were examined for their potential anti-malarial activities. A comprehensive screening methods were designed to
Hee Seon Park et al.
Journal of veterinary science, 21(3), e39-e39 (2020-06-02)
There are various Helicobacter species colonizing the stomachs of animals. Although Helicobacter species usually cause asymptomatic infection in the hosts, clinical signs can occur due to gastritis associated with Helicobacter in animals. Among them, Helicobacter pylori is strongly associated with
Alicja Warowicka et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 64, 152919-152919 (2019-08-30)
It has been shown that secondary metabolites occur in Chelidonium majus L. (C. majus) crude extract and milky sap (alkaloids such as berberine, coptisine, chelidonine, chelerythrine, sanguinarine, and protopine) are biologically active compounds with a wide spectrum of pharmacological functions.
Sabyasachi Chatterjee et al.
Molecular bioSystems, 13(5), 1000-1009 (2017-04-14)
All messenger RNAs (mRNAs) have a polyadenylic acid tail that is added during post transcriptional RNA processing. Investigation of the structure-function and interactions of polyadenylic acid is an important area to target for cancer and related diseases. Jatrorrhizine and coptisine
Alicja Warowicka et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 64, 152919-152919 (2019-08-30)
It has been shown that secondary metabolites occur in Chelidonium majus L. (C. majus) crude extract and milky sap (alkaloids such as berberine, coptisine, chelidonine, chelerythrine, sanguinarine, and protopine) are biologically active compounds with a wide spectrum of pharmacological functions.

Nasz zespół naukowców ma doświadczenie we wszystkich obszarach badań, w tym w naukach przyrodniczych, materiałoznawstwie, syntezie chemicznej, chromatografii, analityce i wielu innych dziedzinach.

Skontaktuj się z zespołem ds. pomocy technicznej