SAB5700581

Anti-Phospho-CSF1R-Y723 antibody produced in rabbit

• Synonim(y): BANDDOS, C-FMS, CD115, CSF-1R, CSF1R, CSFR, FIM2, FMS, HDLS, M-CSF-R
• Kod UNSPSC: 12352203
• NACRES: NA.41

Właściwości

• pochodzenie biologiczne: rabbit
• Poziom jakości: 100
• forma przeciwciała: affinity isolated antibody
• rodzaj przeciwciała: primary antibodies
• klon: polyclonal
• Postać: buffered aqueous solution
• masa cząsteczkowa: 107; 33
• reaktywność gatunkowa: human
• stężenie: 0.76mg/ml
• metody: western blot: 1:500-1:2000
• numer dostępu UniProt: P07333
• Warunki transportu: wet ice
• temp. przechowywania: −20°C
• docelowa modyfikacja potranslacyjna: phosphorylation (pTyr723)
• informacje o genach: human ... CSF1R(1436)

Opis

Opis ogólny

The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants. Expression of a splice variant from an LTR promoter has been found in Hodgkin lymphoma (HL), HL cell lines and anaplastic large cell lymphoma.

Immunogen

A phospho synthetic peptide corresponding to residues surrounding Y723 of human CSF1R.

Postać fizyczna

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Przechowywanie i stabilność

Store at -20℃. Avoid freeze / thaw cycles.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 12 - Non Combustible Liquids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable