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Sigma-Aldrich

Apolipoprotein B, Human Plasma, Low-Density Lipoprotein

Native apolipoprotein B from human plasma. It is a dominant protein constituent of LDL and VLDL. Acts as a ligand for LDL receptor, directing clearance of LDL from plasma to the liver.

Synonim(y):

Apo B, Apo B-100

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About This Item

Kod UNSPSC:
12352202
NACRES:
NA.25

Poziom jakości

Próba

≥95% (SDS-PAGE)

Postać

solid

producent / nazwa handlowa

Calbiochem®

warunki przechowywania

OK to freeze

Warunki transportu

ambient

temp. przechowywania

−20°C

Opis ogólny

Native apolipoprotein B from human plasma. Native apoplipoprotein B from human plasma. Dominant protein constituent of LDL and also present in VLDL. Ligand for the LDL receptor, directing clearance of LDL from plasma to the liver. Functions as a cofactor in enzymatic reactions. Produced by the liver. Mean serum concentration: 950 µg/ml.
Native apolipoprotein B from human plasma. Produced by the liver, and is a dominant protein constituent of LDL that is also present in VLDL. Ligand for LDL receptor, directing clearance of LDL from plasma to the liver. Functions as a cofactor in enzymatic reactions. Mean serum concentration: 950 µg/ml. Higher levels are reported in familial hyperlipidemia, obesity, and diabetes.

Ostrzeżenie

Toxicity: Standard Handling (A)

Postać fizyczna

Lyophilized from 50 mM Na₂CO₃, 50 mM NaCl, 10 mM sodium deoxycholate, pH 10.0.

Uwaga dotycząca przygotowania

Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Rekonstytucja

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Please refer to the label for lot-specific reconstitution volume.

Inne uwagi

Jiang, X.C., et al. 2001. Nat. Med.1, 847.
Zhou, M., et al. 1995. J. Biol. Chem.270, 25220.
Sivaram, P., et al. 1993. J. Biol. Chem.269, 9409.
Sato, R., et al. 1990. J. Biol. Chem. 265, 11880.

Informacje prawne

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Oświadczenie o zrzeczeniu się odpowiedzialności

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
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Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 1

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable


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Odwiedź Bibliotekę dokumentów

Andrzej S Pitek et al.
PloS one, 7(7), e40685-e40685 (2012-07-26)
It is now well established that the surface of nanoparticles (NPs) in a biological environment is immediately modified by the adsorption of biomolecules with the formation of a protein corona and it is also accepted that the protein corona, rather

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