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Merck

S9637

Sigma-Aldrich

Sodium succinate dibasic hexahydrate

BioReagent, suitable for cell culture, suitable for insect cell culture

Synonim(y):

Butanedioic acid disodium salt, Succinic acid disodium salt

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About This Item

Wzór liniowy:
NaOOCCH2CH2COONa · 6H2O
Numer CAS:
Masa cząsteczkowa:
270.14
Beilstein:
3921044
Numer WE:
Numer MDL:
Kod UNSPSC:
12352207
Identyfikator substancji w PubChem:
NACRES:
NA.71
rozpuszczalność:
H2O: 100 mg/mL, clear, colorless

linia produktu

BioReagent

Poziom jakości

metody

cell culture | insect: suitable
cell culture | mammalian: suitable

pH

8—9.5 (25 °C, 270 g/L)

rozpuszczalność

H2O: 100 mg/mL, clear, colorless

ciąg SMILES

O.O.O.O.O.O.[Na+].[Na+].[O-]C(=O)CCC([O-])=O

InChI

1S/C4H6O4.2Na.6H2O/c5-3(6)1-2-4(7)8;;;;;;;;/h1-2H2,(H,5,6)(H,7,8);;;6*1H2/q;2*+1;;;;;;/p-2

Klucz InChI

ZBTUYCUNQBRXOR-UHFFFAOYSA-L

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Opis ogólny

Sodium succinate dibasic hexahydrate is the sodium salt of succinic acid, a dicarboxylic acid. This versatile compound finds extensive use in cell biology, cell culture, and biochemical research applications. It serves as both an energy source and a buffer in cell culture and cell biology research, particularly within the Tricarboxylic Acid (TCA) or Krebs cycle. It is hypothesized that Sodium succinate dibasic hexahydrate acts as an ionophore, facilitating the transport of ions across cell membranes and thus influencing cellular metabolism. Also known as Succinic acid disodium salt, this product provides the necessary substrate for ATP (adenosine triphosphate) production, essential for optimal cellular function.

Zastosowanie

Sodium succinate dibasic hexahydrate has been used:
  • as a supplement in the assay medium to incubate mitochondria to measure the specific activity of complex-II
  • as a component in plant induction medium/ protoplast induction media (PIM) for plant regeneration
  • as a small-molecule additive in the fresh medium to study its positive synergistic effects on transgene expression in Chinese hamster ovary (CHO) cells

Cechy i korzyści

  • Versatile and adaptable for a wide variety of laboratory and research applications
  • BioReagent Grade Sodium succinate for your Cell Biology and Biochemical research
  • Tested for Mammalian and Insect cell culture applications

Inne uwagi

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Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 1

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

Środki ochrony indywidualnej

dust mask type N95 (US), Eyeshields, Gloves


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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Adrián Povo-Retana et al.
Cancers, 12(10) (2020-10-24)
Tumor-associated macrophages (TAMs) play a crucial role in suppressing the immunosurveillance function of the immune system that prevents tumor growth. Indeed, macrophages can also be targeted by different chemotherapeutic agents improving the action over immune checkpoints to fight cancer. Here
Jun Kimura et al.
Cancer science, 104(8), 1083-1090 (2013-05-18)
Pancreatic cancer has a poor prognosis after complete macroscopic resection combined with chemotherapy. Even after neoadjuvant chemotherapy, R0 resection is often not possible. Moreover, current imaging techniques cannot reliably distinguish viable cancer cells from scar tissue at the resectional margin.
Ilya B Zavodnik et al.
Life sciences, 92(23), 1110-1117 (2013-05-07)
The present study was designed for further evaluation of the biochemical mechanism of hepatic mitochondrial dysfunction under oxidative damages induced by organic hydroperoxide, tert-butyl hydroperoxide (tBHP), for estimation of the molecular targets impaired during oxidative stress, and for investigation of
Hiroshi Yoneyama et al.
Anti-cancer drugs, 26(1), 90-100 (2014-09-05)
The efficacy of gemcitabine (GEM), a standard treatment agent for pancreatic cancer, is insufficient because of primary or acquired resistance to this drug. Patients with tumors intrinsically sensitive to GEM gradually acquire resistance and require a shift to second agents

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