O2260

Osteopontin from mouse

>95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture

• Synonim(y): Bone Sialoprotein-1, Early T Lymphocyte Activation Protein-1 (ETA-1), OPN, Secreted Phosphoprotein 1 (Spp1)
• Numer MDL: MFCD03100698
• Kod UNSPSC: 12352202
• NACRES: NA.32

Właściwości

• pochodzenie biologiczne: mouse
• Poziom jakości: 100
• rekombinowane: expressed in NSO cells
• sterylność: sterile
• Próba: >95% (SDS-PAGE)
• Postać: lyophilized powder
• masa cząsteczkowa: 30 kDa by SDS-PAGE (reducing); 65 kDa by SDS-PAGE (reducing) (doublet)
• opakowanie: pkg of 50 μg
• metody: cell culture | mammalian: suitable
• zanieczyszczenia: endotoxin, tested
• numer dostępu UniProt: P10923
• Warunki transportu: dry ice
• temp. przechowywania: −20°C
• informacje o genach: mouse ... Spp1(20750)

Opis

Zastosowanie

Osteopontin from mouse has been used:

• to study its role in a mouse model of preterm brain injury
• as a positive control to analyze the relationship between the vascular calcification process and osteopontin (OPN) overexpression in the neointima of atherosclerotic plaques
• to study its interaction on the crystal growth process of hydroxyapatite in agarose hydrogels

Działania biochem./fizjol.

Osteopontin (OPN) is a secreted, highly acidic, calcium binding, phosphorylated glycoprotein that is chemotactic for macrophages, smooth muscle cells, endothelial cells and glial cells. In activated macrophages, OPN inhibits nitric oxide production and cytotoxicity. Human, mouse, rat, pig and bovine OPN share 40% amino acid sequence identity.

Postać fizyczna

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 2.5 mg bovine serum albumin.

Komentarz do analizy

The biological activity is measured by its ability to mediate 293 cell adhesion.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable