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Key Documents

I1656

Sigma-Aldrich

Idarubicin hydrochloride

solid

Synonim(y):

(7S-cis)-9-Acetyl-7-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-5,12-naphthacenedione, 4-Demethoxydaunorubicin hydrochloride, DMDR, IMI-30, Idamycin

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About This Item

Wzór empiryczny (zapis Hilla):
C26H27NO9 · HCl
Numer CAS:
57852-57-0
Masa cząsteczkowa:
533.95
Numer WE:
260-990-7
Numer MDL:
MFCD00866457
Kod UNSPSC:
12352200
Identyfikator substancji w PubChem:
24278488
NACRES:
NA.77

Postać

solid

Poziom jakości

200

inicjator

Johnson & Johnson

Warunki transportu

wet ice

temp. przechowywania

2-8°C

ciąg SMILES

[H][C@@]1(C[C@@](O)(Cc2c(O)c3C(=O)c4ccccc4C(=O)c3c(O)c12)C(C)=O)O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5

InChI

1S/C26H27NO9/c1-10-21(29)15(27)7-17(35-10)36-16-9-26(34,11(2)28)8-14-18(16)25(33)20-19(24(14)32)22(30)12-5-3-4-6-13(12)23(20)31/h3-6,10,15-17,21,29,32-34H,7-9,27H2,1-2H3/t10-,15-,16-,17-,21+,26-/m0/s1

Klucz InChI

XDXDZDZNSLXDNA-TZNDIEGXSA-N

informacje o genach

human ... TOP2A(7153)

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Zastosowanie

Idarubicin is an anthracycline antibiotic that is an anti-leukemia agent with higher DNA binding capacity and greater cytotoxicity than daunorubicin.

Działania biochem./fizjol.

Topoisomerase II inhibitor

Cechy i korzyści

This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
This page may contain text that has been machine translated.

Piktogramy

Skull and crossbonesHealth hazard
GHS06,GHS08

Hasło ostrzegawcze

Danger

Zwroty wskazujące rodzaj zagrożenia

H300,H351,H360

Zwroty wskazujące środki ostrożności

P201 - P301 + P310 + P330

Klasyfikacja zagrożeń

Acute Tox. 2 Oral - Carc. 2 - Repr. 1B

Kod klasy składowania

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Klasa zagrożenia wodnego (WGK)

WGK 3

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

Środki ochrony indywidualnej

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Certyfikaty analizy (CoA)

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