E6754
Epoxy-activated−Sepharose™ 6B
lyophilized powder
Synonim(y):
Epoxy-activated-Agarose
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About This Item
Polecane produkty
Formularz
lyophilized powder
zakres etykietowania
19-40 μmol per mL
metody
affinity chromatography: suitable
Matryca
Sepharose 6B
grupa aktywna macierzy
epoxy
MAR
through epoxy to hydroxyl
spacer macierzy
12 atoms
pęcznienie
1 g swells to 3.0-5.0 mL
wielkość cząstki
45—165 μm
temp. przechowywania
2-8°C
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Opis ogólny
when ligands are coupled to free epoxy groups. Linkage is a stable, uncharged ether.
Zastosowanie
Epoxy-activated-Sepharose™ is used in affinity chromatography, protein chromatography, and activated/functionalized matrices. Epoxy-activated-Sepharose™ has been used to obtain a monoclonal antibody against the prokaryotically expressed foot-and-mouth disease virus (FMDV) non-structural protein (NSP) 3B as well as to study B meningococcal disease.
Inne uwagi
Ligand: 1,4-bis(2:3-Epoxypropoxy)butane
Attachment: one epoxy group
Spacer: provides a 12-atom spacer when ligands are coupled to free epoxy groups. Linkage is a stable, uncharged ether.
Attachment: one epoxy group
Spacer: provides a 12-atom spacer when ligands are coupled to free epoxy groups. Linkage is a stable, uncharged ether.
Postać fizyczna
Lyophilized powder
Informacje prawne
Sepharose is a trademark of Cytiva
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zastąpiony przez
Numer produktu
Opis
Cennik
Kod klasy składowania
11 - Combustible Solids
Klasa zagrożenia wodnego (WGK)
WGK 3
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
Środki ochrony indywidualnej
Eyeshields, Gloves, type N95 (US)
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We have previously demonstrated that tamoxifen and related triphenylethylene compounds are potent inhibitors of protein kinase C (PKC). The present study demonstrates that PKC binds specifically and reversibly to the antiestrogen N-didesmethyltamoxifen when the drug is coupled to CNBr-activated agarose
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A monoclonal antibody, 3BIgG, against the prokaryotically expressed foot-and-mouth disease virus (FMDV) non-structural protein (NSP) 3B was obtained. The 3BIgG-sepharose conjugant (3BmAb-6BFF) was prepared by adding the purified 3BIgG into epoxy-activated sepharose 6BFF, incubating with the inactivated FMDV, and then
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