Wszystkie zdjęcia(3)
Kluczowe dokumenty
D9761
6-Deoxy-D-glucose
Synonim(y):
D-Isorhamnose, Epifucose, Quinovose
Zaloguj sięWyświetlanie cen organizacyjnych i kontraktowych
About This Item
Wzór empiryczny (zapis Hilla):
C6H12O5
Numer CAS:
Masa cząsteczkowa:
164.16
Beilstein:
1723317
Numer WE:
Numer MDL:
Kod UNSPSC:
12352200
Identyfikator substancji w PubChem:
NACRES:
NA.52
Polecane produkty
klasa czystości
Molecular Biology
for molecular biology
Poziom jakości
Próba
≥98% (TLC)
Formularz
powder
temp. przechowywania
−20°C
ciąg SMILES
C[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O
InChI
1S/C6H12O5/c1-2-3(7)4(8)5(9)6(10)11-2/h2-10H,1H3/t2-,3-,4+,5-,6?/m1/s1
Klucz InChI
SHZGCJCMOBCMKK-GASJEMHNSA-N
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Opis ogólny
6-Deoxy-D-glucose is a structural homolog of D-glucose (dextrose) and stable analog. It lacks the hydroxyl group at carbon 6 position. It is also an analog of mannose.
Zastosowanie
6-Deoxy-D-glucose has been used as a standard in the circular dichroism measurements. It has also been used as sugar to incubate starved Dictyostelium HMX44A.atg1-1 cells for microscopy studies.
Działania biochem./fizjol.
2-Deoxy-D-glucose (2-DG) is used as a glycolytic inhibitor in studying the biological function of glucose. It is not metabolized, induces endoplasmic reticulum stress and hence, blocks the carbohydrate metabolism in cancer cells. It has therapeutic potential in targeting chemo-resistant hypoxic cancer cells. 2-DG halts the N-linked glycosylation by replacing mannose.
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Kod klasy składowania
11 - Combustible Solids
Klasa zagrożenia wodnego (WGK)
WGK 3
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
Środki ochrony indywidualnej
Eyeshields, Gloves, type N95 (US)
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