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D1156

Sigma-Aldrich

N,N-Dimethylglycine

≥99%, suitable for ligand binding assays

Synonim(y):

(Dimethylamino)acetic acid

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About This Item

Wzór liniowy:
(CH3)2NCH2COOH
Numer CAS:
1118-68-9
Masa cząsteczkowa:
103.12
Beilstein:
1700261
Numer WE:
214-267-8
Numer MDL:
MFCD00004283
Kod UNSPSC:
12352209
eCl@ss:
32160406
Identyfikator substancji w PubChem:
24893366
NACRES:
NA.26

product name

N,N-Dimethylglycine, ≥99%

Poziom jakości

200

Próba

≥99%

Postać

powder

metody

ligand binding assay: suitable

kolor

white to off-white

mp

178-182 °C (lit.)

Zastosowanie

peptide synthesis

ciąg SMILES

CN(C)CC(O)=O

InChI

1S/C4H9NO2/c1-5(2)3-4(6)7/h3H2,1-2H3,(H,6,7)

Klucz InChI

FFDGPVCHZBVARC-UHFFFAOYSA-N

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Działania biochem./fizjol.

N,N-Dimethylglycine (DMG) is a natural N-methylated glycine that is used in comparative analysis with other N-methylated glycines such as sarcosine and βine. N,N-Dimethylglycine is used in the development of glycine-based ionic liquids and emulsifiers. N,N-Dimethylglycine is potentially useful as a biomarker of protein degradation in COPD patients. DMG is used as a substrate to identify, differentiate and characterize amino acid methyltransferase(s).
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Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 3

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

Środki ochrony indywidualnej

Eyeshields, Gloves, type N95 (US)

Certyfikaty analizy (CoA)

Poszukaj Certyfikaty analizy (CoA), wpisując numer partii/serii produktów. Numery serii i partii można znaleźć na etykiecie produktu po słowach „seria” lub „partia”.

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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Baljit K Ubhi et al.
The European respiratory journal, 40(2), 345-355 (2011-12-21)
There is a paucity of biomarkers for chronic obstructive pulmonary disease (COPD). Metabolomics were applied to a defined COPD patient cohort from the ECLIPSE study (Evaluation of COPD Longitudinally to Identify Predictive Surrogate End-points). Results were correlated with accepted biomarkers
S H Moolenaar et al.
Clinical chemistry, 45(4), 459-464 (1999-04-02)
A38-year-old man presented with a history of fish odor (since age 5) and unusual muscle fatigue with increased serum creatine kinase. Our aim was to identify the metabolic error in this new condition. We used 1H NMR spectroscopy to study
B A Binzak et al.
American journal of human genetics, 68(4), 839-847 (2001-03-07)
Dimethylglycine dehydrogenase (DMGDH) (E.C. number 1.5.99.2) is a mitochondrial matrix enzyme involved in the metabolism of choline, converting dimethylglycine to sarcosine. Sarcosine is then transformed to glycine by sarcosine dehydrogenase (E.C. number 1.5.99.1). Both enzymes use flavin adenine dinucleotide and
Michael Lever et al.
PloS one, 7(5), e37883-e37883 (2012-06-01)
Betaine insufficiency is associated with unfavourable vascular risk profiles in metabolic syndrome patients. We investigated associations between betaine insufficiency and secondary events in acute coronary syndrome patients. Plasma (531) and urine (415) samples were collected four months after discharge following
Isabelle D Kalmar et al.
The British journal of nutrition, 107(11), 1635-1644 (2011-09-21)
N,N-Dimethylglycine (DMG) is a tertiary amino acid that naturally occurs as an intermediate metabolite in choline-to-glycine metabolism. The objective of the present trial was to evaluate tolerance, safety and bioaccumulation of dietary DMG in broilers when supplemented at 1 g
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