C0625

Caffeic acid

≥98.0% (HPLC)

• Synonim(y): 3,4-Dihydroxybenzeneacrylic acid, 3,4-Dihydroxycinnamic acid, 3-(3,4-Dihydroxyphenyl)-2-propenoic acid
• Wzór liniowy: (HO)₂C₆H₃CH=CHCO₂H
• Numer CAS: 331-39-5
• Masa cząsteczkowa: 180.16
• Beilstein: 1954563
• Numer WE: 206-361-2
• Numer MDL: MFCD00004392
• Kod UNSPSC: 12352106
• Identyfikator substancji w PubChem: 24278290
• NACRES: NA.77

Właściwości

• Próba: ≥98.0% (HPLC)
• Postać: powder
• mp: 211-213 °C (dec.) (lit.)
• rozpuszczalność: ethanol: 50 mg/mL
• Zastosowanie: metabolomics; vitamins, nutraceuticals, and natural products
• ciąg SMILES: OC(=O)\C=C\c1ccc(O)c(O)c1
• InChI: 1S/C9H8O4/c10-7-3-1-6(5-8(7)11)2-4-9(12)13/h1-5,10-11H,(H,12,13)/b4-2+
• Klucz InChI: QAIPRVGONGVQAS-DUXPYHPUSA-N
• informacje o genach: human ... ELA2(1991) ; rat ... Alox5(25290)

Opis

Opis ogólny

Caffeic acid exists in its free and ester form. It is considered as the predominant polyphenol, contributing to the hydroxycinnamic acid content in various fruits. Coffee is one of the major source of caffeic acid.

Zastosowanie

Caffeic acid has been used as a standard of phenolic acid in the study to determine the total phenolic acid content in vegetables after subjecting to alkaline and acid hydrolysis. It has also been used to determine its antioxidant activity by various assay methods.

Działania biochem./fizjol.

A natural dietary phenolic compound found in plants that is an anti-oxidant. Inhibits the synthesis of leukotrienes that are involved in immunoregulation, inflammation and allergy. Inhibits Cu²⁺-induced LDL oxidation.

Caffeic acid and other polyphenols are metabolized by going through enzyme catalysed methyl transfer, sulfation and glucuronic acid addition. It non-competitively prevents the action of 5-lipoxygenase. Caffeic acid ready undergoes hydrolysis in alkaline conditions.

Cechy i korzyści

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS08
• Hasło ostrzegawcze: Warning
• Zwroty wskazujące rodzaj zagrożenia: H351
• Zwroty wskazujące środki ostrożności: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Klasyfikacja zagrożeń: Carc. 2
• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable
• Środki ochrony indywidualnej: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges