Wszystkie zdjęcia(1)
Kluczowe dokumenty
A9210
Annexin V FITC Conjugate from human placenta
Synonim(y):
Annexin V, Calphosbindin I, Lipocortin V, PAP-1
Zaloguj sięWyświetlanie cen organizacyjnych i kontraktowych
About This Item
Kod UNSPSC:
41106305
NACRES:
NA.32
Polecane produkty
Formularz
buffered aqueous solution
Poziom jakości
zakres etykietowania
1-2 mol FITC per mol annexin V
numer dostępu UniProt
Warunki transportu
wet ice
temp. przechowywania
2-8°C
informacje o genach
human ... ANXA5(308)
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Zastosowanie
For detection of apoptotic cells by flow cytometry or fluorescence microscopy.
Działania biochem./fizjol.
Annexins are ubiquitous homologous proteins that bind phospholipids in the presence of calcium. The cellular changes involved in the apoptotic process include loss of phospholipid asymmetry during the early stages. This phenomenon is universal and is not limited to stimulus or to mammalian cells, but also occurs in insect and plant cells. In living cells, phosphatidylserine is transported to the inside of the lipid bilayer by the Mg2+ATP dependent enzyme, aminophospholipid translocase. At the onset of apoptosis, phosphatidylserine becomes translocated to the external surface of the cell membrane. Since the movement of phosphatidylserine from the internal membrane surface to the external surface is an early indicator of apoptosis, annexin V and its conjugates that interact strongly and specifically with phosphatidylserine may be used to detect apoptosis. Annexin V conjugates can be used to detect apoptotic cells significantly earlier than DNA-based assays. Fluorescent dye labeled annexin V have applications in flow cytometry, fluorescence microscopy, and laser scanning cytometry.
Opakowanie
Package size based on protein content
Postać fizyczna
Solution in 50 mM Tris-HCl, pH 7.5, containing 100 mM NaCl.
Ta strona może zawierać tekst przetłumaczony maszynowo.
Kod klasy składowania
12 - Non Combustible Liquids
Klasa zagrożenia wodnego (WGK)
WGK 1
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
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