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94646

Sigma-Aldrich

Poly(ethylene glycol)

BioUltra, 35,000

Synonim(y):

Polyethylene glycol, PEG

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About This Item

Wzór liniowy:
H(OCH2CH2)nOH
Numer CAS:
25322-68-3
Numer MDL:
MFCD00081839
Kod UNSPSC:
12352104
Identyfikator substancji w PubChem:
24890034
NACRES:
NA.26

Poziom jakości

200

linia produktu

BioUltra

Postać

powder or crystals (or flakes)

masa cząsteczkowa

Mr ~35000

zanieczyszczenia

insoluble matter:, passes filter test
≤0.005% peroxides (as H2O2):

pH

5.5-7.0 (25 °C, 50 mg/mL in H2O)

mp

64-66 °C

rozpuszczalność

H2O: 50 mg/mL at 25 °C, clear, colorless

ślady anionów

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤50 mg/kg

ślady kationów

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤200 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤200 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

λ

50 mg/mL in H2O

absorpcja UV

λ: 260 nm Amax: 0.12
λ: 280 nm Amax: 0.12

ciąg SMILES

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

Klucz InChI

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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Opis ogólny

Polyethylene glycol (PEG) is a polyether compound that is used as an additive in cosmetics, pharmaceuticals, and food. It consists of repeated ethylene glycol units[-(CH2CH2O)n].

Zastosowanie

Poly(ethylene glycol) has been used:
  • as a component of University of Wisconsin (UW) cold preservation solutions to stabilize the cell membrane of hepatocytes during temperature changes
  • as a component of the supercooling solution to study supercooling preservation technique of the rat liver for transplantation and to protect against hypothermic injury
  • to prepare aqueous phase for the fabrication of multicellular spheroid (MCS) cultures

Działania biochem./fizjol.

Polyethylene glycol (PEG) is a synthetic polymer that is used as a gold standard in bioconjugation and nanomedicine to extend blood circulation time and enhance drug efficacy. It acts as an ice-modulator by preventing ice crystallization, which is beneficial for cellular membranes. PEG provides protection against hypothermic injury, like lipid peroxidation and cell membrane injury. PEG-conjugated drugs are considered safe for use in humans and are approved by the U.S. Food and Drug Administration (FDA). PEG has several biomedical applications, including biosensing, imaging, and tissue engineering. It also repels protein adsorption and lowers the liver uptake, which helps in coating nanoparticles.
This page may contain text that has been machine translated.

Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 1

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

Środki ochrony indywidualnej

Eyeshields, Gloves, type N95 (US)

Certyfikaty analizy (CoA)

Poszukaj Certyfikaty analizy (CoA), wpisując numer partii/serii produktów. Numery serii i partii można znaleźć na etykiecie produktu po słowach „seria” lub „partia”.

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Polyethylene glycol (PEG) is a polymer of choice in drug delivery systems. This USFDA-approved polymer is popular due to its tunable properties and well-established safety profile: prime requisites considered during the selection of any excipient in formulation development. The unique
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