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Merck

P2139

Sigma-Aldrich

Poly(ethylene glycol)

average MN 8,000, hydroxyl

Synonim(y):

Glikol polietylenowy

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About This Item

Wzór liniowy:
H(OCH2CH2)nOH
Numer CAS:
Numer MDL:
Kod UNSPSC:
12352104
Identyfikator substancji w PubChem:
NACRES:
NA.23

Nazwa produktu

Poly(ethylene glycol), average mol wt 8,000, powder

Formularz

powder

masa cząsteczkowa

average mol wt 8,000

rozpuszczalność

water: soluble (PEG is soluble in water approximately 630 mg/ml, 20 °C)

gęstość

1.0845 g/mL at 70 °C
1.0689 g/mL at 90 °C

Ω-koniec

hydroxyl

α-koniec

hydroxyl

ciąg SMILES

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

Klucz InChI

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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Opis ogólny

Polyethylene glycol (PEG) is a hydrophilic polymer. It can be easily synthesized by the anionic ring opening polymerization of ethylene oxide, into a range molecular weights and variety of end groups. When crosslinked into networks PEG can have high water content, forming “hydrogels”. PEG is a suitable material for biological applications because it does not trigger an immune response

Zastosowanie

Poly (ethylene glycol) can be used in the formulation of the drug to improve its dissolution rate and oral bioavailability.

PEG can be used for the effective isolation of edible nanoparticles (ENPs) which have excellent anti-cancer and anti-inflammatory activities. PEG is a crowding agent and forms a net-like mesh in which nanovesicles are trapped and precipitated. For example, ginger-derived ENPs are isolated using a PEG-based method which is cost-effective compared to ultracentrifugation.

PEG can be used as a precursor to synthesize degradable hydrogels for the controlled release of hydrophilic and high molecular weight pharmaceuticals.

Cechy i korzyści

  • Highstructural flexibility
  • Biocompatibility
  • Amphiphilicity
  • Highhydration capacity
  • Devoidof any steric hindrance
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Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 1

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

Środki ochrony indywidualnej

Eyeshields, Gloves, type N95 (US)


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