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90081
3-O-Methylquercetin
≥97% (HPLC)
Synonim(y):
5,7,3′ ,4′ -Tetrahydroxy-3-methoxyflavone, Quercetin 3-O-methyl ether
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About This Item
Wzór empiryczny (zapis Hilla):
C16H12O7
Numer CAS:
Masa cząsteczkowa:
316.26
Beilstein:
324509
Numer MDL:
Kod UNSPSC:
12352202
Identyfikator substancji w PubChem:
NACRES:
NA.32
Polecane produkty
Poziom jakości
Próba
≥97% (HPLC)
Formularz
powder
ciąg SMILES
COC1=C(Oc2cc(O)cc(O)c2C1=O)c3ccc(O)c(O)c3
InChI
1S/C16H12O7/c1-22-16-14(21)13-11(20)5-8(17)6-12(13)23-15(16)7-2-3-9(18)10(19)4-7/h2-6,17-20H,1H3
Klucz InChI
WEPBGSIAWZTEJR-UHFFFAOYSA-N
Działania biochem./fizjol.
3-O-Methylquercetin significantly inhibits cyclic adenosine monophosphate- (cAMP-) and cyclic guanosine monophosphate- (cGMP-) phosphodiesterase activity. It possess anti-inflammatory, bronchodilating properties and used in treatment of asthma. It suppresses the total inflammatory cells, tumor necrosis factor-α (TNF-α) and attenuates the production of interleukins.
3-O-Methylquercetin is a metabolite in flavone and flavonol biosynthesis. It is a naturally occurring compound present in various plants, and was shown to have potent anticancer-promoting, antioxidant, antiallergy, and antimicrobial activity, and showed strong anti-viral activity inhibition of tomato ringspot virus.
Opakowanie
Bottomless glass bottle. Contents are inside inserted fused cone.
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Hasło ostrzegawcze
Danger
Zwroty wskazujące rodzaj zagrożenia
Zwroty wskazujące środki ostrożności
Klasyfikacja zagrożeń
Acute Tox. 3 Oral
Kod klasy składowania
6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
Klasa zagrożenia wodnego (WGK)
WGK 3
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
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3-O-methylquercetin more selectively inhibits phosphodiesterase subtype 3
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The aim of this study was to investigate the potential of quercetin and two of its "in vivo" metabolites, 3'-O-methyl quercetin and 4'-O-methyl quercetin, to protect H9c2 cardiomyoblasts against H(2)O(2)-induced oxidative stress. As limited data are available regarding the potential
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Dietary antioxidants interact in a dynamic fashion, including recycling and sparing one another, to decrease oxidative stress. Limited information is available regarding the interrelationships in vivo between quercetin and vitamin E. We investigated the antioxidant activity and metabolism of quercetin
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