483R-1

p40 (ZR8) Rabbit Monoclonal Antibody

• Kod UNSPSC: 12352203
• klon: ZR8
• application: IHC (p)
• reaktywność gatunkowa: human
• metody: immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable (1:100-1:200 (concentrated))
• citations: 8

Właściwości

• pochodzenie biologiczne: rabbit
• Poziom jakości: 100; 500
• białko sprzężone: unconjugated
• forma przeciwciała: culture supernatant
• rodzaj przeciwciała: primary antibodies
• klon: ZR8
• opis: For In Vitro Diagnostic Use in Select Regions
• Formularz: buffered aqueous solution
• reaktywność gatunkowa: human
• opakowanie: vial of 0.1 mL concentrate (483R-14); vial of 0.1 mL concentrate, Research Use Only (483R-14-RUO); vial of 0.5 mL concentrate (483R-15); vial of 1.0 mL concentrate (483R-16); vial of 1.0 mL concentrate, Research Use Only (483R-16-RUO); vial of 1.0 mL pre-dilute, Research Use Only (483R-17-RUO); vial of 1.0 mL pre-dilute, ready to use (483R-17); vial of 25.0 mL pre-dilute, ready-to-use (483R-10); vial of 25.0 mL pre-dilute, ready-to-use, Research Use Only (483R-10-RUO); vial of 7.0 mL pre-dilute, ready to use (483R-18); vial of 7.0 mL pre-dilute, ready to use, Research Use Only (483R-18-RUO)
• producent / nazwa handlowa: Cell Marque
• metody: immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable (1:100-1:200 (concentrated))
• izotyp: IgG
• kontrola: lung (squamous cell carcinoma), prostate, urothelial carcinoma
• Warunki transportu: wet ice
• temp. przechowywania: 2-8°C
• wizualizacja: nuclear

Opis

Opis ogólny

p40 is an isoform of p63, a transcription factor that regulates many cell activities, including cell proliferation, maintenance, and differentiation. It performs as a sensitive and specific tool for aiding in the identification of squamous cell carcinoma of the lung. In addition to its utility as a squamous differentiation marker, p40 has also been proven to be a valuable marker for highlighting myoepithelial and basal cell populations in prostate, breast, skin, and salivary gland.^1-5 Strong p40 expression is frequently observed in esophageal cancerous squamous lesions.⁶ Immunohistochemical detection of p40 can also be helpful in identifying urothelial carcinoma.⁷ In cases of prostate carcinoma, p40 is almost always found to be negative for basal cell staining.⁸

Jakość

• United States - IVD
• Canada - RUO
• European Union - IVD
• Japan - RUO

Postać fizyczna

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Uwaga dotycząca przygotowania

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Inne uwagi

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 12 - Non Combustible Liquids
• Klasa zagrożenia wodnego (WGK): WGK 2
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable