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Wzór empiryczny (zapis Hilla):
C11H11FN2O2
Numer CAS:
Masa cząsteczkowa:
222.22
Beilstein:
5052680
Numer MDL:
Kod UNSPSC:
12352202
eCl@ss:
32160406
Identyfikator substancji w PubChem:
NACRES:
NA.77
Polecane produkty
Próba
≥98.0% (HPLC)
Formularz
powder
czystość optyczna
enantiomeric ratio: ≥99.5:0.5 (HPLC)
mp
270-280 °C
temp. przechowywania
2-8°C
ciąg SMILES
N[C@@H](Cc1c[nH]c2ccc(F)cc12)C(O)=O
InChI
1S/C11H11FN2O2/c12-7-1-2-10-8(4-7)6(5-14-10)3-9(13)11(15)16/h1-2,4-5,9,14H,3,13H2,(H,15,16)/t9-/m0/s1
Klucz InChI
INPQIVHQSQUEAJ-VIFPVBQESA-N
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Zastosowanie
Exogenous 5-fluoro-Trp is incorporated into proteins in normal protein synthesis. Since 19F is a useful reporter group, this provides a method for studying enzyme mechanisms by NMR.
Działania biochem./fizjol.
5-Fluoro-Trp is nonspecifically cytotoxic. It is believed this is due to malfunctioning enzymes that have had replacements of Trp residues by 5-fluoro-Trp. However, at least one case is known where 5-fluoro-Trp substitution leads to significantly greater catalytic activity.
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Kod klasy składowania
11 - Combustible Solids
Klasa zagrożenia wodnego (WGK)
WGK 3
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
Środki ochrony indywidualnej
Eyeshields, Gloves, type N95 (US)
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