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280C-1

Sigma-Aldrich

Mammaglobin Cocktail (304-1A5 & 31A5)

Mouse & Rabbit Cocktail Antibody

Synonim(y):

Mammaglobin Cocktail (304-1A5 & 31A5) Mouse/Rabbit Monoclonal Antibodies

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About This Item

Kod UNSPSC:
12352203
NACRES:
NA.41
klon:
304-1A5/31A5, monoclonal
application:
IHC
reaktywność gatunkowa:
human
metody:
immunohistochemistry: 1:100-1:500
citations:
6

pochodzenie biologiczne

mouse
rabbit

Poziom jakości

100
300
500

białko sprzężone

unconjugated

forma przeciwciała

purified immunoglobulin

rodzaj przeciwciała

primary antibodies

klon

304-1A5/31A5, monoclonal

opis

For In Vitro Diagnostic Use in Select Regions (See Chart).

Formularz

buffered aqueous solution

reaktywność gatunkowa

human

opakowanie

vial of 0.1 mL concentrate (280C-14-ASR)
vial of 0.5 mL concentrate (280C-15-ASR)
bottle of 1.0 mL predilute (280C-17-ASR)
vial of 1.0 mL concentrate (280C-16-ASR)
bottle of 7.0 mL predilute (280C-18-ASR)

stężenie

0.01-1 μg/mL (predilute)
2-270 μg/mL (concentrate)

metody

immunohistochemistry: 1:100-1:500

izotyp

IgG1
IgG

Warunki transportu

wet ice

temp. przechowywania

2-8°C

informacje o genach

human ... SCGB2A2(4250)

Opis ogólny

Mammaglobin (10 kD) is a breast-associated glycoprotein distantly related to secretoglobin family that includes human uteroglobin and lipophilin. Mammaglobin mRNA is present in high levels in human breast cancer cell lines, which has been shown to be a sensitive marker of breast cancer. When combined with other breast-restricted markers such as GCDFP-15, an overall sensitivity for breast carcinoma of 84% has been achieved. Anti-Mammaglobin can also be used to determine breast origin in the setting of metastatic carcinoma.

Jakość


IVD
IVD
IVD
RUO

Postać fizyczna

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

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Inne uwagi

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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Zhiqiang Wang et al.
International journal of clinical and experimental pathology, 2(4), 384-389 (2009-01-23)
Identification of metastasis and occult micrometastases of breast cancer demands sensitive and specific diagnostic markers. In this study, we assessed the utility of a mouse monoclonal antibody to human mammaglobin for one such purpose. Immunohistochemical stains were performed on paraffin-embedded
Jae-Ho Han et al.
Archives of pathology & laboratory medicine, 127(10), 1330-1334 (2003-10-03)
Organ specificity is a desirable property of a tumor marker, especially in metastatic adenocarcinomas of unknown primary origin. Mammaglobin, a mammary-specific member of the uteroglobin family, is known to be overexpressed in human breast cancer. We investigated mammaglobin A expression
T P Fleming et al.
Annals of the New York Academy of Sciences, 923, 78-89 (2001-02-24)
The mammaglobin gene encodes a 10-kDa glycoprotein that is distantly related to a family of proteins that includes rat estramustine binding protein (EMBP)/prostatein and human Clara cell 10-kDa protein (CC10)/uteroglobin. Among normal adult tissues, mammaglobin mRNA expression has been detected
Rohit Bhargava et al.
American journal of clinical pathology, 127(1), 103-113 (2006-12-06)
There are limited data that compare the usefulness of mammaglobin with gross cystic disease fluid protein-15 (GCDFP-15) in the identification of breast carcinomas. Whole tissue sections of 29 breast carcinomas with matched lymph node metastases and 63 breast carcinomas on
Eiichi Sasaki et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 20(2), 208-214 (2006-12-29)
Previously, we used the reverse transcription-polymerase chain reaction (RT-PCR) to show that mammaglobin (MGB1) can serve as a differential marker of breast cancer metastasis from primary lung cancer. However, mRNA-based methods are not appropriate for use in clinical practices. In
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