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Inne dokumenty

Y0001079

Benserazide for peak identification

European Pharmacopoeia (EP) Reference Standard

Synonim(y):

Benserazide hydrochloride, DL-Serine 2-(2,3,4-trihydroxybenzyl)hydrazide hydrochloride

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About This Item

Wzór empiryczny (zapis Hilla):
C10H15N3O5 · HCl
Numer CAS:
14919-77-8
Masa cząsteczkowa:
293.70
Numer MDL:
MFCD00078571
Kod UNSPSC:
41116107
Identyfikator substancji w PubChem:
329831250
NACRES:
NA.24

klasa czystości

pharmaceutical primary standard

producent / nazwa handlowa

EDQM

Zastosowanie

pharmaceutical (small molecule)

format

neat

temp. przechowywania

2-8°C

ciąg SMILES

Cl.NC(CO)C(=O)NNCc1ccc(O)c(O)c1O

InChI

1S/C10H15N3O5.ClH/c11-6(4-14)10(18)13-12-3-5-1-2-7(15)9(17)8(5)16;/h1-2,6,12,14-17H,3-4,11H2,(H,13,18);1H

Klucz InChI

ULFCBIUXQQYDEI-UHFFFAOYSA-N

informacje o genach

human ... DDC(1644)

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Opis ogólny

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Zastosowanie

Benserazide for peak identification EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Działania biochem./fizjol.

Inhibitor of L-aromatic amino acid decarboxylase.

Opakowanie

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Inne uwagi

Sales restrictions may apply.
This page may contain text that has been machine translated.

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Certyfikaty analizy (CoA)

Lot/Batch Number

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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Wai Kin D Ko et al.
Neurobiology of disease, 70, 138-148 (2014-06-28)
Regulators of G-protein signalling (RGS) proteins are implicated in striatal G-protein coupled receptor (GPCR) sensitisation in the pathophysiology of l-DOPA-induced abnormal involuntary movements (AIMs), also known as dyskinesia (LID), in Parkinson's disease (PD). In this study, we investigated RGS protein
Jacob Wienecke et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(36), 11984-12000 (2014-09-05)
Serotonin (5-HT), an important modulator of both sensory and motor functions in the mammalian spinal cord, originates mainly in the raphe nuclei of the brainstem. However, following complete transection of the spinal cord, small amounts of 5-HT remain detectable below
Sylvia Navailles et al.
CNS neuroscience & therapeutics, 20(7), 671-678 (2014-04-30)
Serotonin (5-HT) neurons mediate the ectopic release of dopamine (DA) induced by L-DOPA in the Parkinsonian brain. We hypothesized that the participation of noradrenalin transporters (NET) in the clearance of DA may account for the lower effect of L-DOPA in
Dalila Mango et al.
Experimental neurology, 261, 733-743 (2014-09-01)
γ-Aminobutyric acid A receptor (GABAAR)-mediated postsynaptic currents were recorded in brain slices from substantia nigra pars reticulate neurons. The selective adenosine A1 receptor (A1R) antagonist, 8-cyclopentyl-1,3-dipropylxanthine (DPCPX), increased the frequency, but not the amplitude of spontaneous inhibitory post-synaptic currents (IPSCs)
Yong Wang et al.
Synapse (New York, N.Y.), 68(8), 332-343 (2014-03-07)
l-3,4-Dihydroxyphenylalanine (L-DOPA) is the most widely used drug for the treatment of Parkinson's disease. Unfortunately, chronic administration of this dopamine precursor causes L-DOPA-induced dyskinesia (LID), which is a debilitating complication whose pathogenesis remains unclear. In this study, we compared gene
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