PHR1078

Phytonadione

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonim(y): Vitamin K₁, Phytomenadione, 2-Methyl-3-phytyl-1,4-naphthoquinone, 3-Phytylmenadione, Phylloquinone, Vitamin K₁₍₂₀₎
• Wzór empiryczny (zapis Hilla): C₃₁H₄₆O₂
• Numer CAS: 84-80-0
• Masa cząsteczkowa: 450.70
• Beilstein: 2568816
• Numer WE: 201-564-2
• Numer MDL: MFCD00214063
• Kod UNSPSC: 41116107
• Identyfikator substancji w PubChem: 329823101
• NACRES: NA.24

Właściwości

• klasa czystości: certified reference material; pharmaceutical secondary standard
• Poziom jakości: 300
• agency: traceable to BP 423; traceable to Ph. Eur. P1609000; traceable to USP 1538006
• rodzina API: phytonadione
• Certyfikat analizy: current certificate can be downloaded
• warunki przechowywania: protect from light
• metody: HPLC: suitable; gas chromatography (GC): suitable
• współczynnik refrakcji: n20/D 1.527 (lit.)
• mp: −20 °C (lit.)
• gęstość: 0.984 g/mL at 25 °C (lit.)
• Zastosowanie: pharmaceutical (small molecule)
• format: neat
• temp. przechowywania: 2-8°C
• ciąg SMILES: O=C(C1=CC=CC=C21)C(C)=C(C/C=C(CCC[C@@H](CCC[C@H](C)CCCC(C)C)C)\C)C2=O
• InChI: 1S/C31H46O2/c1-22(2)12-9-13-23(3)14-10-15-24(4)16-11-17-25(5)20-21-27-26(6)30(32)28-18-7-8-19-29(28)31(27)33/h7-8,18-20,22-24H,9-17,21H2,1-6H3/b25-20+/t23-,24-/m1/s1
• Klucz InChI: MBWXNTAXLNYFJB-NKFFZRIASA-N

Opis

Opis ogólny

Phytonadione belongs to the category of oral anticonvulsant drugs. It protects a newborn from acquiring hemorrhagic diseases by maintaining a normal blood clotting mechanism.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Zastosowanie

Phytonadione may be used as a pharmaceutical reference standard in the determination of the analyte in pharmaceutical formulations by chromatographic and spectrophotometric techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Komentarz do analizy

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Inne uwagi

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Values of analytes vary lot to lot.

Przypis

To see an example of a Certificate of Analysis for this material enter LRAB3714 in the slot below. This is an example certificate only and may not be the lot that you receive.

This page may contain text that has been machine translated.

Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 10 - Combustible liquids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable