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I0460000

Isoleucine

European Pharmacopoeia (EP) Reference Standard

Synonim(y):

L-Isoleucine, (2S,3S)-2-Amino-3-methylpentanoic acid

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About This Item

Wzór liniowy:
C2H5CH(CH3)CH(NH2)CO2H
Numer CAS:
73-32-5
Masa cząsteczkowa:
131.17
Beilstein:
1721792
Numer MDL:
MFCD00064222
Kod UNSPSC:
41116107
Identyfikator substancji w PubChem:
329815310
NACRES:
NA.24

klasa czystości

pharmaceutical primary standard

rodzina API

leucine

producent / nazwa handlowa

EDQM

mp

288 °C (dec.) (lit.)

Zastosowanie

pharmaceutical (small molecule)

Format

neat

temp. przechowywania

2-8°C

ciąg SMILES

CC[C@H](C)[C@H](N)C(O)=O

InChI

1S/C6H13NO2/c1-3-4(2)5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t4-,5-/m0/s1

Klucz InChI

AGPKZVBTJJNPAG-WHFBIAKZSA-N

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Opis ogólny

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Zastosowanie

Isoleucine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Opakowanie

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Inne uwagi

Sales restrictions may apply.
Ta strona może zawierać tekst przetłumaczony maszynowo.

Kod klasy składowania

13 - Non Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 1

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

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Certyfikaty analizy (CoA)

Lot/Batch Number

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L-Isoleucine BioUltra, ≥99.5% (NT)

Sigma-Aldrich

58879

L-Isoleucine

L-Isoleucine from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 98.5-101.0%

Sigma-Aldrich

I7403

L-Isoleucine

D-Isoleucine ≥98% (TLC)

Sigma-Aldrich

I7634

D-Isoleucine

DL-allo-Isoleucine ≥99.0%

Sigma-Aldrich

05706

DL-allo-Isoleucine

L-izoleucyna for biochemistry

Millipore

1.05362

L-izoleucyna

L-Leucine from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 98.5-101.0%

Sigma-Aldrich

L8912

L-Leucine

Proline European Pharmacopoeia (EP) Reference Standard

P3350000

Proline

L-Leucine reagent grade, ≥98% (HPLC)

Sigma-Aldrich

L8000

L-Leucine

O Søvik
Journal of inherited metabolic disease, 16(1), 46-54 (1993-01-01)
A review is presented of 22 published cases of verified or probable mitochondrial 2-methylacetoacetyl-CoA thiolase deficiency, a disorder of isoleucine and ketone body metabolism. The clinical expression, characterized by ketoacidosis, vomiting and lethargy, is highly variable. Typical age of onset
Stanley H Korman
Molecular genetics and metabolism, 89(4), 289-299 (2006-09-05)
Three inborn errors have been identified in the pathway of isoleucine degradation. Deficiency of beta-ketothiolase (beta-KT, also known as T2, mitochondrial acetoacetyl-CoA thiolase and acetyl-CoA acetyltransferase 1) is a well-described disorder which presents with acute episodic ketoacidosis. In contrast, short/branched-chain
O A Mamer
Journal of chromatography. B, Biomedical sciences and applications, 758(1), 49-55 (2001-08-03)
The initial catabolic steps of isoleucine by mammals has been misunderstood and misapprehended in the scientific literature for many years. The suggestion that the interconversion of isoleucine and alloisoleucine occurs through the keto-enol racemization of their respective transaminated alpha-keto acids
Vijay Joshi et al.
Amino acids, 39(4), 933-947 (2010-02-27)
Pathways regulating threonine, methionine and isoleucine metabolism are very efficiently interconnected in plants. As both threonine and methionine serve as substrates for isoleucine synthesis, their synthesis and catabolism under different developmental and environmental conditions also influence isoleucine availability. Together, methionine
Jirí Svoboda et al.
Phytochemistry, 71(13), 1445-1449 (2010-06-24)
Our understanding of plant defensive mechanisms against herbivore and pathogen attack has significantly increased over the past decade. The complex cascade of defensive events is initiated and controlled by a network of interacting plant hormones. Especially, the conjugate of jasmonate
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Protokoły

GC Analysis of Amino Acids (as TBDMS Derivatives) on SLB®-5ms (20 m x 0.18 mm I.D., 0.18 μm), Fast GC Analysis

Separation of L-Alanine; Glycine; L-Valine; L-Leucine; L-Isoleucine; L-Proline; L-Methionine; L-Serine; L-Threonine; L-Phenylalanine; L-Aspartic acid; L-4-Hydroxyproline; L-Cysteine; L-Glutamic acid; L-Asparagine; L-Lysine; L-Glutamine; L-Histidine; L-Tyrosine; L-Tryptophan; L-Cystine

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