BP1094

Cyclophosphamide

British Pharmacopoeia (BP) Reference Standard

• Synonim(y): Cyclophosphamide monohydrate, 2-[Bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide, Cytoxan
• Wzór empiryczny (zapis Hilla): C₇H₁₅Cl₂N₂O₂P · H₂O
• Numer CAS: 6055-19-2
• Masa cząsteczkowa: 279.10
• Beilstein: 4678992
• Numer MDL: MFCD00149395
• Kod UNSPSC: 41116107
• NACRES: NA.24

Właściwości

• klasa czystości: pharmaceutical primary standard
• rodzina API: cyclophosphamide
• Postać: crystalline
• okres trwałości: limited shelf life, expiry date on the label
• producent / nazwa handlowa: BP
• mp: 49-51 °C (lit.)
• Zastosowanie: pharmaceutical; pharmaceutical small molecule
• format: neat
• temp. przechowywania: 2-8°C
• ciąg SMILES: [H]O[H].ClCCN(CCCl)P1(=O)NCCCO1
• InChI: 1S/C7H15Cl2N2O2P.H2O/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14;/h1-7H2,(H,10,12);1H2
• Klucz InChI: PWOQRKCAHTVFLB-UHFFFAOYSA-N

Opis

Opis ogólny

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Zastosowanie

Cyclophosphamide BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:

Cyclophosphamide Oral Solution

Działania biochem./fizjol.

Cyclophosphamide is a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity.

Opakowanie

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

Inne uwagi

Sales restrictions may apply.

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS06,GHS08
• Hasło ostrzegawcze: Danger
• Zwroty wskazujące rodzaj zagrożenia: H301,H340,H350,H360FD
• Zwroty wskazujące środki ostrożności: P202 - P264 - P270 - P280 - P301 + P310 - P405
• Klasyfikacja zagrożeń: Acute Tox. 3 Oral - Carc. 1B - Muta. 1B - Repr. 1A
• Kod klasy składowania: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): 235.4 °F - closed cup
• Temperatura zapłonu (°C): 113 °C - closed cup