MAB1598
Anti-Post Synaptic Density Protein 95 Antibody, clone 7E3-1B8
clone 7E3-1B8, Chemicon®, from mouse
Synonim(y):
PSD-95
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About This Item
Kod UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Polecane produkty
pochodzenie biologiczne
mouse
Poziom jakości
forma przeciwciała
purified immunoglobulin
rodzaj przeciwciała
primary antibodies
klon
7E3-1B8, monoclonal
reaktywność gatunkowa
bovine, rat, mouse
reaktywność gatunkowa (przewidywana na podstawie homologii)
human
producent / nazwa handlowa
Chemicon®
metody
immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
izotyp
IgG1
numer dostępu UniProt
Warunki transportu
dry ice
docelowa modyfikacja potranslacyjna
unmodified
informacje o genach
bovine ... Dlg4(100137840)
human ... DLG4(1742)
mouse ... Dlg4(13385)
rat ... Dlg4(29495)
Opis ogólny
The postsynaptic density (PSD) is an electron dense structure just beneath the postsynaptic membrane. Several functions have been proposed for the PSD including regulating receptor number and clustering, anchoring signal transduction molecules at the synapse and mediating adhesion between the presynaptic and postsynaptic membranes. The most abundant PSD protein is the [alpha] subunit of the type II calcium/calmodulin dependent protein kinase ([alpha]CaMKII). This protein is likely to play a role in the calcium-mediated signal transduction at the synapse that mediates certain forms of synaptic plasticity. Another major PSD protein is PSD-95, a member of the guanylate kinase family (GUK) of proteins.
Specyficzność
Reacts with recombinant rat PSD-95 and identifies a band at approximately ~100 kDa, corresponding to PSD-95, on western blots of rat brain, mouse brain and bovine brain extracts. Also present in rat brain and mouse brain tissue extracts are bands of approximately 80 kDa and 50 kDa. PSD-95 is believed to initiate NMDA receptor clustering on the post synaptic membrane.
Immunogen
Recombinant rat PSD-95
Zastosowanie
Anti-Post Synaptic Density Protein 95 Antibody, clone 7E3-1B8 is an antibody against Post Synaptic Density Protein 95 for use in IC, IP & WB.
Immunocytochemistry:
A previous lot of this antibody was used in IC.
Immunoprecipitation:
A previous lot of this antibody was used in IP.
Optimal working dilutions must be determined by the end user.
A previous lot of this antibody was used in IC.
Immunoprecipitation:
A previous lot of this antibody was used in IP.
Optimal working dilutions must be determined by the end user.
Jakość
Evaluated by Western Blot on Mouse brain lysates.
Western Blot Analysis:
1:500 dilution of this antibody detected PSD-95 on 10 µg of Mouse brain lysates.
Western Blot Analysis:
1:500 dilution of this antibody detected PSD-95 on 10 µg of Mouse brain lysates.
Opis wartości docelowych
~ 95 kDa
Powiązanie
Replaces: 04-1066
Postać fizyczna
Format: Purified
Purified mouse monoclonal IgG1 liquid in buffer containing PBS, pH 7.2, with 0.09% sodium azide and 50% glycerol.
Komentarz do analizy
Control
Mouse brain, rat brain tissue
Mouse brain, rat brain tissue
Inne uwagi
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Informacje prawne
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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polecane
Kod klasy składowania
10 - Combustible liquids
Klasa zagrożenia wodnego (WGK)
WGK 2
Certyfikaty analizy (CoA)
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Masz już ten produkt?
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