8.52310

Fmoc-SDMA(Boc)2-ONa

Novabiochem^®

• Synonim(y): Fmoc-SDMA(Boc)2-ONa, N-α-Fmoc-N,NÆ-δ-dimethyl-N,NÆ-δ-di-t.-butoxycarbonyl-L-arginine sodium salt
• Wzór empiryczny (zapis Hilla): C₃₃H₄₃N₄NaO₈
• Masa cząsteczkowa: 646.71
• Kod UNSPSC: 12352209
• NACRES: NA.22

Właściwości

• Poziom jakości: 200
• linia produktu: Novabiochem^®
• Próba: ≥90.0% (HPLC)
• Postać: powder
• przydatność reakcji: reaction type: Fmoc solid-phase peptide synthesis
• producent / nazwa handlowa: Novabiochem^®
• Zastosowanie: peptide synthesis
• grupa funkcyjna: Boc; Fmoc
• temp. przechowywania: -10 to -25°C

Opis

Opis ogólny

A derivative for the introduction of symmetric dimethyl-arginine during Fmoc SPPS. Coupling can be carried out using any standard activation method. Removal of the Boc protecting groups occurs during the course of the TFA-mediated cleavage reaction. Ref ^[1] contains methods and protocols for the synthesis of arrays of histone-related peptides containing methylated arginine and lysine-residues.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Guide to Selection of Orthogonally -Protected Building Blocks for Fmoc SPPS

Literature references

^[1] S. Rothbart, et al. (2012) Methods Enzymol., 512, 107.

Komentarz do analizy

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Assay (HPLC, area%): ≥ 90.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Informacje prawne

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable