440153

L-α-lysophosphatidylinositol sodium salt

>99% (HPLC), powder, GPR55 agonist, Calbiochem^®

• Synonim(y): L-α-lysophosphatidylinositol Sodium Salt, Soy, L-α-lysophosphatidylinositol LPI, Lyso PI, Soy Lyso PI
• Wzór empiryczny (zapis Hilla): C₂₅H₄₈NaO₁₂P
• Numer CAS: 796963-91-2
• Masa cząsteczkowa: 594.61
• Kod UNSPSC: 12352200
• NACRES: NA.77

Właściwości

• product name: L-α-lysophosphatidylinositol Sodium Salt, Soy, A potent agonist and assumed endogenous ligand of GPR55.
• Poziom jakości: 100
• Próba: >99% (HPLC)
• Postać: powder
• producent / nazwa handlowa: Calbiochem^®
• warunki przechowywania: OK to freeze; desiccated (hygroscopic); protect from light
• kolor: white
• rozpuszczalność: DMSO: soluble
• Warunki transportu: ambient
• temp. przechowywania: −20°C
• ciąg SMILES: O[C@H]1[C@H](OP(OC[C@H](O)COC(CCCCCCCCCCCCCCC)=O)([O-][Na+])=O)[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O

Opis

Opis ogólny

A potent agonist and assumed endogenous ligand of GPR55, shown to induce rapid phosphorylation of p38 mitogen-activated protein kinase (MAPK) and its downstream activating transcription factor 2 (ATF2) in both GPR55-transfected HEK293 cells, and in IM-9 lymphoblastoid cells naturally expressing GPR55 at 1 µM, while having no effect on vector-transfected cells. In addition, shown to enhance serum induced cell migration in MCF-7 cells over expressing GPR55.

A potent agonist and assumed endogenous ligand of GPR55, shown to induce rapid phosphorylation of p38 mitogen-activated protein kinase (MAPK) and its downstream activating transcription factor 2 (ATF2) in both GPR55-transfected HEK293 cells, and in IM-9 lymphoblastoid cells naturally expressing GPR55 at 1uM, while having no effect on vector-transfected cells. In addition, shown to enhance serum induced cell migration in MCF-7 cells over expressing GPR55.

Opakowanie

Packaged under inert gas

Ostrzeżenie

Toxicity: Standard Handling (A)

Inne uwagi

Oka, S., et al. 2010. J Biochem.147, 671.
Oka, S., et al. 2007.
Biochem. Biophys. Res. Commun.362, 928.

Informacje prawne

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 2
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable