234138
Human Collagen Type I
from human skin, powder
Synonim(y):
Collagen, Type I, Human Skin
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About This Item
Polecane produkty
Nazwa produktu
Collagen, Type I, Human Skin,
pochodzenie biologiczne
human skin
Poziom jakości
Próba
≥95% (SDS-PAGE)
Formularz
lyophilized
producent / nazwa handlowa
Calbiochem®
warunki przechowywania
OK to freeze
dilution
(compatible for the preparation of collagen gels)
zanieczyszczenia
≤0.1% subdermal hair
rozpuszczalność
acetic acid: 5 mg/mL (0.5M)
Warunki transportu
ambient
temp. przechowywania
2-8°C
Opis ogólny
Collagen type 1 is a fibrillar collagen present abundantly in skin, bone, vasculature, and calcified tissues of teeth and bone. It is also seen in organs like the heart and lungs. Collagen type 1 is a heterotrimer consisting of two α1 (CIα1) and one α2 (CIα2) chains with a helical region made of repeating units of proline and hydroxyproline.
Zastosowanie
Collagen Type I, Human Skin has been used as a skin protein to study the effect of age-related NADH oxidase (ar-NOX)-catalyzed oxidation on skin proteins. It has also been used as a control sample in High-resolution mass spectrometry (HRMS) analysis.
Działania biochem./fizjol.
Collagen type 1 is a main component of the dermal extracellular matrix (ECM) and participates in skin elasticity. Mutations in collagen type 1 are associated with osteogenesis imperfecta and Ehlers–Danlos syndrome.
Ostrzeżenie
Toxicity: Standard Handling (A)
Postać fizyczna
Salt-free.
Uwaga dotycząca przygotowania
Prepared from tissue of individuals that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Rekonstytucja
The recommended concentration is 0.01 to 0.5 M Acetic Acid (or another acidic buffer), with a maximum concentration of 5 mg/ml. The product has been tested at 0.5 M Acetic Acid and is stable for 1 month at 2-8°C. After reconstitution, aliquot and freeze at -20°C. Stock solutions remain stable for up to 6 months at this temperature.
Inne uwagi
Gallop, P.M., and Siefert, S. 1963. Methods Enzymol. 6, 635.
Informacje prawne
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Oświadczenie o zrzeczeniu się odpowiedzialności
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
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Kod klasy składowania
11 - Combustible Solids
Klasa zagrożenia wodnego (WGK)
WGK 1
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
Certyfikaty analizy (CoA)
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