870865P

BMP22

Avanti Polar Lipids, powder

• Synonim(y): 4-pentadecylbenzylphosphonic acid
• Wzór empiryczny (zapis Hilla): C₂₂H₃₉O₃P
• Numer CAS: 1306684-90-1
• Masa cząsteczkowa: 382.52
• Kod UNSPSC: 12352211

Właściwości

• Próba: 99% (TLC)
• Postać: powder
• opakowanie: pkg of 1 × 1 mg (870865P-1mg); pkg of 1 × 5 mg (870865P-5mg)
• producent / nazwa handlowa: Avanti Polar Lipids
• typ lipidu: bioactive lipids
• Warunki transportu: dry ice
• temp. przechowywania: −20°C
• ciąg SMILES: CCCCCCCCCCCCCCCC1=CC=C(CP(O)(O)=O)C=C1

Opis

Opis ogólny

BMP (bis(monoacylglycerol)phosphate) is synthesized from phosphatidylglycerol (PG) in alveolar macrophages. BMP is a unique phospholipid having a glycerol phosphate ester at sn-1 position rather than sn-3 and has one acyl group attached to each of the glycerol moieties. The acyl groups of BMP is rich in polyunsaturated species.

Działania biochem./fizjol.

BMP (bis(monoacylglycerol)phosphate) (BMP) is found in the retinal pigment epithelium of healthy human retina. BMP lipids regulates cholesterol level in endosomes. It is implicated in endosomal/lysosomal storage diseases like Niemann-Pick and neuronal ceroid lipofuscinosis diseases. BMP22/4PBPA is a small molecule inhibitor of autotaxin (ATX). 4PBPA has relatively a longer half-life and also reduces the lysophosphatidic acid concentration in plasma. BMP22 is implicated in reducing the bone erosion and systemic bone loss.

Opakowanie

5ML Glass Amber Screw Cap Vial (870865P-1MG)

5ML Glass Amber Screw Cap Vial (870865P-5MG)

Informacje prawne

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable