QBD10850

Thiol-dPEG^®₁₂-acid

>95% (HPLC)

• Synonim(y): CT(PEG)₁₂, Carboxy-PEG-Thiol, Carboxy-PEG₁₂-Thiol, HS-PEG₁₂-COOH, Thiol-PEG₁₂-acid
• Wzór empiryczny (zapis Hilla): C₂₇H₅₄O₁₄S
• Masa cząsteczkowa: 634.77
• Numer MDL: MFCD21363238
• Kod UNSPSC: 12162002
• NACRES: NA.22

Właściwości

• Próba: >95% (HPLC)
• Postać: solid or viscous liquid
• przydatność reakcji: reaction type: Pegylations
• architektura polimerowa: shape: linear; functionality: heterobifunctional
• Warunki transportu: ambient
• temp. przechowywania: −20°C

Opis

Cechy i korzyści

Thiol-dPEG₁₂-acid is a single molecular weight, discrete-length polyethylene glycol (dPEG) crosslinking PEGylation reagent. One end of the crosslinker terminates in a sulfhydryl (thiol) group. Propionic acid terminates the opposite end. The thiol end of the molecule forms dative bonds with gold. Moreover, it forms thioether bonds with maleimide and bromoacetate groups and disulfide bonds with other sulfhydryl groups. The propionic acid group reacts with amines to form amide bonds. Alternatively, if it is left unreacted, the propionic acid group provides a negative charge to the conjugated molecule or modified surface. The monodispersed dPEG spacer is 39 atoms (46.8 Å) long.

Informacje prawne

Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681

dPEG is a registered trademark of Quanta BioDesign

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable