907324

Fmoc-L-photo-proline

≥95%

• Synonim(y): (S)-5-(((9H-Fluoren-9-yl)methoxy)carbonyl)-1,2,5-triazaspiro[2.4]hept-1-ene-6-carboxylic acid, (S)-5-Fmoc-1,2,5-triazaspiro[2.4]hept-1-ene-6-carboxylic acid, Diazirine amino acid, Photo-Pro, Photo-crosslinking amino acid, Photoprobe building block
• Wzór empiryczny (zapis Hilla): C₂₀H₁₇N₃O₄
• Numer CAS: 1266778-58-8
• Masa cząsteczkowa: 363.37
• Numer MDL: MFCD31380718
• Kod UNSPSC: 12352209

Właściwości

• Próba: ≥95%
• Postać: powder
• przydatność reakcji: reaction type: Fmoc solid-phase peptide synthesis
• mp: 113-116 °C
• Zastosowanie: peptide synthesis
• grupa funkcyjna: Fmoc
• temp. przechowywania: −20°C

Opis

Zastosowanie

Fmoc-L-photo-proline is a diazirine-containing, Fmoc-protected proline amino acid and multifunctional probe building blocks. Its incorporation into peptides or small-molecule probes and tools allows for photoaffinity labeling of cellular targets and protein-protein interactions upon UV light (∼360 nm) irradiation to form a covalent bond. This and other multifunctional probe building blocks will continue to accelerate drug discovery research for probing cellular mechanisms, target ID/validation, and understanding traditionally undruggable targets. An unprotected version is also available as 907286.

Product can be used with our line of photoreactors: Including Penn PhD (Z744035) & SynLED 2.0 (Z744080)

Inne uwagi

Chemical Probes Unravel an Antimicrobial Defense Response Triggered by Binding of the Human Opioid Dynorphin to a Bacterial Sensor Kinase

Peptidomimetic Antibiotics Target Outer-Membrane Biogenesis in Pseudomonas aeruginosa

Fishing for Drug Targets: A Focus on Diazirine Photoaffinity Probe Synthesis

Photo-affinity labeling (PAL) in chemical proteomics: a handy tool to investigate protein-protein interactions (PPIs)

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS02
• Hasło ostrzegawcze: Danger
• Zwroty wskazujące rodzaj zagrożenia: H242
• Zwroty wskazujące środki ostrożności: P210 - P234 - P235 - P240 - P370 + P378 - P403
• Klasyfikacja zagrożeń: Self-react. C
• Kod klasy składowania: 5.2 - Organic peroxides and self-reacting hazardous materials
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable