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Sigma-Aldrich

Poly(2-ethyl-2-oxazoline) 5-7 cSt

Synonim(y):

Poly(2-ethyl-2-oxazoline), PEOX, POx, PetOx, poly 2-ethyloxazoline, polyethyloxazoline

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About This Item

Wzór liniowy:
[-N(COC2H5)CH2CH2-]n
Numer CAS:
25805-17-8
Numer MDL:
MFCD00134377
Kod UNSPSC:
12162002
Identyfikator substancji w PubChem:
329755635
NACRES:
NA.23

Postać

solid

Poziom jakości

200

masa cząsteczkowa

average Mw ~50,000

współczynnik refrakcji

n20/D 1.52

lepkość

5-7 cSt, 10 % in water(100 °F)

temp. przejścia

softening point 110-120 °C (Vicat, ASTM D 1525-82)
Tg 69-71 °C

gęstość

1.14 g/mL at 25 °C (lit.)

PDI

3‑4

InChI

1S/C5H9NO/c1-2-5-6-3-4-7-5/h2-4H2,1H3

Klucz InChI

NYEZZYQZRQDLEH-UHFFFAOYSA-N

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Zastosowanie

This Poly(2-ethyl-2-oxazoline) polymer is amorphous and water soluble with good temperature stability. Jordan and coworkers showed biocompatibility, no accumulation in tissue, and rapid clearance from the bloodstream. End-group modified poly(2-ethyl-2-oxazoline)s have been conjugated to peptides, and were shown as versatile alternatives to poly(ethylene glycol) (PEG) for both protein and small drug conjugation.

Potential substitute for poly(vinyl alcohol) and poly(vinyl pyrrolidone). Adhesion promoter in coatings. Heat sealing and remoistenable hot-melt adhesive

Cechy i korzyści

Nonionic, water-soluble thermoplastic. Better heat stability than poly(vinyl alcohol). Good melt flow, shear stability and Newtonian characteristics. Water is a room temperature Theta solvent.

Postać fizyczna

N-propionyl substituted linear polyethylenimine
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Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 3

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

Środki ochrony indywidualnej

Eyeshields, Gloves, type N95 (US)

Wybierz jedną z najnowszych wersji:

Certyfikaty analizy (CoA)

Lot/Batch Number
MKCQ8239
MKCN8244
MKCL1856
MKCK6568
MKCH2049

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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Yung-Chu Chen et al.
Journal of biomedical materials research. Part A, 100(5), 1279-1292 (2012-03-01)
The multifunctional nanoparticles constructed from triphenylamine-poly(lactide-co-glycolide)-poly(ethyleneglycol)-poly(lactide-co-glycolide) (TPA-PEP) and folate-poly(2-ethyl-2oxazoline)-poly(D,L-lactide) (folate-PEOz-PLA) were developed in this study. Iron oxide nanoparticles (IOP) and paclitaxel (PTX) were coencapsulated in the nanoparticles with diameter less than 200 nm. The drug-loaded nanoparticles emit fluorescence peak at
I C Kwon et al.
Nature, 354(6351), 291-293 (1991-11-28)
New controlled drug-delivery systems are being explored to overcome the disadvantages of conventional dosage forms. For example, stimulated drug-delivery has been used to overcome the tolerance problems that occur with a constant delivery rate, to mimic the physiological pattern of
Chau-Hui Wang et al.
Journal of controlled release : official journal of the Controlled Release Society, 108(1), 140-149 (2005-09-27)
Polymeric micelles based on poly(L-lactide)-b-poly(2-ethyl-2-oxazoline)-b-poly(L-lactide) (PLLA-PEOz-PLLA) ABA triblock copolymers were designed as intracellular drug carriers. The PLLA-PEOz-PLLA micelles adopt a "flower-like" arrangement with A-blocks at the core and a B-block on the shell under neutral condition. The deformation of the
Chau-Hui Wang et al.
Biomacromolecules, 4(6), 1487-1490 (2003-11-11)
A new series of cationic, thermo-sensitive, and biodegradable poly(L-lactide)-poly(2-ethyl-2-oxazoline)-poly(L-lactide) (PLLA-PEOz-PLLA) triblock copolymers were synthesized by ring-opening polymerization. With increasing molecular weight and crystallinity of hydrophobic PLLA blocks, the critical micellization concentrations (CMC) occurred at lower concentration. The PLLA-PEOz-PLLA aqueous solution
S R Winn et al.
Orthodontics & craniofacial research, 8(3), 183-190 (2005-07-19)
Bone repair strategies continue to be developed for alternatives to autografting, allogeneic implants of banked bone, and other bone substitutes. Efforts have included the delivery of potent growth and/or differentiation factors and the use of gene therapy. For bone regeneration
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