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169102
1-Docosanol
98%
Synonim(y):
Behenyl alcohol
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About This Item
Polecane produkty
Poziom jakości
Próba
98%
tw
180 °C/0.22 mmHg (lit.)
mp
65-72 °C (lit.)
grupa funkcyjna
hydroxyl
ciąg SMILES
CCCCCCCCCCCCCCCCCCCCCCO
InChI
1S/C22H46O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23/h23H,2-22H2,1H3
Klucz InChI
NOPFSRXAKWQILS-UHFFFAOYSA-N
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Opis ogólny
1-Docosanol inhibits replication of certain viruses (herpes simplex virus and respiratory syncytial virus) within primary target cells in vitro. It has been isolated from Clematis brevicaudata.
Zastosowanie
1-Docosanol was used in the synthesis of series of amphiphilic dendrimers with hydrophilic aliphatic polyether-type dendritic core and hydrophobic docosyl peripheries.
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Kod klasy składowania
11 - Combustible Solids
Klasa zagrożenia wodnego (WGK)
nwg
Temperatura zapłonu (°F)
410.0 °F
Temperatura zapłonu (°C)
210 °C
Środki ochrony indywidualnej
Eyeshields, Gloves, type N95 (US)
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Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 32(10), 1534-1537 (2010-02-02)
To study the chemical constituents from Clematis brevicaudata. The compounds were isolated by column chromatography and their structures were elucidated through spectroscopic analysis (NMR). Eight compounds were isolated and identified as: palmitic acid (1), 1-docosanol (2), pentacosanoic acid-2', 3'-dihydroxypropyl ester
Synthesis and self-assembly of amphiphilic dendrimers based on aliphatic polyether-type dendritic cores.
Macromolecules, 37(11), 4227-4234 (2004)
Antiviral activity of 1-docosanol, an inhibitor of lipid-enveloped viruses including herpes simplex.
Proceedings of the National Academy of Sciences of the United States of America, 88(23), 10825-10829 (1991-12-01)
This article reports that 1-docosanol, a 22-carbon-long saturated alcohol, exerts a substantial inhibitory effect on replication of certain viruses (e.g., herpes simplex virus and respiratory syncytial virus) within primary target cells in vitro. To study the basis for its viral
Antiviral research, 56(2), 153-166 (2002-10-09)
Interactions between docosanol (n-docosanol, behenyl alcohol) and nucleoside or pyrophosphate analogs were investigated in vitro. The anti-HSV activity of acyclovir (ACV) was synergistically enhanced by treatment of cells with docosanol as judged by inhibition of progeny virus production and plaque
Journal of chemical ecology, 37(4), 329-339 (2011-03-23)
The uropygial secretions of some bird species contain volatile and semivolatile compounds that are hypothesized to serve as chemical signals. The abundance of secretion components varies with age and season, although these effects have not been investigated in many species.
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