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Merck

GRIN2A

glutamate receptor, ionotropic, N-methyl D-aspartate 2A

Synonimy:
EPND, GluN2A, NMDAR2A, NR2A
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(2903) Summary: N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate-gated ion channels. These receptors have been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C) and NMDAR2D (GRIN2D). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
  • Mouse(14811) glutamate receptor, ionotropic, NMDA2A (epsilon 1)
  • Rat(24409) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • chicken(427678) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • dog(490012) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • domestic cat(101086110) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • sheep(101106989) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • domestic guinea pig(100727265) glutamate receptor, ionotropic, N-methyl D-aspartate 2A

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Small Molecule - Agonist

Numer produktu
Opis
Gatunek
1,4-Bis(3-aminopropyl)piperazine, ≥99%,
Gatunek
rat
Dextromethorphan hydrobromide, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
Dextromethorphan HBr, certified reference material, pharmaceutical secondary standard,
Gatunek
human
Dextromethorphan solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Gatunek
human
Dextromethorphan hydrobromide, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human

Small Molecule - Allosteric Modulator

Numer produktu
Opis
Gatunek
4-Aminopiperidine, ,
Gatunek
rat
S-(+)-Ketamine hydrochloride, ,
Gatunek
human
Ketamine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Ketamine hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Gatunek
human
(±)-Ketamine hydrochloride, solid,
Gatunek
human

Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
1-Adamantanemethylamine, 98%,
Gatunek
human
Glycine, meets analytical specification of Ph. Eur., BP, USP, 99-101% (based on anhydrous substance),
Gatunek
rat
Glycine, BioUltra, for molecular biology, ≥99.0% (NT),
Gatunek
rat
Glycine, puriss. p.a., reag. Ph. Eur., buffer substance, 99.7-101% (calc. to the dried substance),
Gatunek
rat
1-Adamantylamine, 97%,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-GRIN2A antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot
Monoclonal Anti-Glun2A/Nr2A antibody produced in mouse, clone S327A-38, purified immunoglobulin,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot
Monoclonal Anti-Glun2A/Nr2A - Apc antibody produced in mouse, clone S327A-38, purified immunoglobulin,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot
Monoclonal Anti-Glun2A/Nr2A - Biotin antibody produced in mouse, clone S327A-38, purified immunoglobulin,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot
Monoclonal Anti-Glun2A/Nr2A - Atto 488 antibody produced in mouse, clone S327A-38, purified immunoglobulin,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot

Small Molecule - Blocker

Numer produktu
Opis
Gatunek
N-(3,3-Diphenylpropyl)glycinamide, >98% (HPLC), solid,
Gatunek
human
Agmatine sulfate salt, ≥97%, powder,
Gatunek
human
Orphenadrine hydrochloride, ≥98.0% (AT),
Gatunek
human
Orphenadrine for peak identification, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Orphenadrine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
Indole-2-carboxylic acid, 98%,
Gatunek
rat, human
1,3-Diphenylguanidine, 97%,
Gatunek
rat, mouse, human
Quisqualic acid, powder,
Gatunek
rat
Nω-Nitro-L-arginine, ≥98% (TLC),
Gatunek
rat, mouse, human
Pentamidine isethionate salt, powder,
Gatunek
human

Small Molecule - Mixed Agonist/Antagonist

Numer produktu
Opis
Gatunek
2,2-Dimethyl-1,3-propanediamine, 99%,
Gatunek
rat
1,3-Diamino-2-propanol, purum, ≥96.5% (GC),
Gatunek
rat
N,N,2,2-Tetramethyl-1,3-propanediamine, 97%,
Gatunek
rat
N,N,N′,N′-Tetramethyl-1,3-propanediamine, ≥99%,
Gatunek
rat
N,N′-Dimethyl-1,3-propanediamine, 97%,
Gatunek
rat

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting mouse Grin2a,
Gatunek
mouse
MISSION® esiRNA, targeting human GRIN2A,
Gatunek
human