1176007

Dexamethasone

United States Pharmacopeia (USP) Reference Standard

• 동의어(들): (11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione, 9α-Fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione, 9α-Fluoro-16α-methylprednisolone, Prednisolone F
• 실험식(Hill 표기법): C₂₂H₂₉FO₅
• CAS Number: 50-02-2
• Molecular Weight: 392.46
• Beilstein: 2066651
• MDL number: MFCD00064136
• UNSPSC 코드: 41116107
• PubChem Substance ID: 329749548
• NACRES: NA.24

속성

• 생물학적 소스: synthetic
• Grade: pharmaceutical primary standard
• Agency: USP
• vapor pressure: <0.0000001 kPa ( 25 °C)
• API family: dexamethasone
• 포장: pkg of 125 mg
• 제조업체/상표: USP
• 색상: white
• mp: 262-264 °C (lit.)
• solubility: acetone: sparingly soluble; chloroform: slightly soluble; ethanol: sparingly soluble; ether: very slightly soluble; methanol: sparingly soluble; water: practically insoluble
• 응용 분야: pharmaceutical (small molecule)
• 형식: neat
• 저장 온도: 2-8°C
• SMILES string: C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
• InChI: 1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1
• InChI key: UREBDLICKHMUKA-CXSFZGCWSA-N
• 유전자 정보: human ... NR3C1(2908)

설명

일반 설명

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

애플리케이션

Dexamethasone Related Compound J USP reference standard for use in specified quality tests and assays.

Also used to prepare system suitability and standard solution during the performance test and impurity analysis by using liquid chromatography in conjunction with UV detector according to the given below monographs of United States Pharmacopeia (USP) :

• Dexamethasone.
• Dexamethasone Tablets.
• Dexamethasone Oral Solution.
• Dexamethasone Sodium Phosphate Ophthalmic Solution.

Dexamethasone USP reference standard may be used as a pharmaceutical primary standard for the determination of the analyte in pharmaceutical formulations, and biological samples by various analytical techniques.

생화학적/생리학적 작용

Glucocorticoid anti-inflammatory agent. Regulates T cell survival, growth, and differentiation. Inhibits the induction of nitric oxide synthase.

분석 메모

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

기타 정보

Sales restrictions may apply.

안전성 정보

• 픽토그램: GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H360FD
• 예방조치 성명서: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Repr. 1B
• Storage Class Code: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable