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Key Documents

D0710000

Dexamethasone acetate

European Pharmacopoeia (EP) Reference Standard

동의어(들):

Dexamethasone 21-acetate, 9α-Fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione-21-acetate, 9α-Fluoro-16α-methylprednisolone-21-acetate, Prednisolone F acetate

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About This Item

실험식(Hill 표기법):
C24H31FO6
CAS Number:
Molecular Weight:
434.50
Beilstein:
2342608
MDL number:
UNSPSC 코드:
41116107
PubChem Substance ID:
NACRES:
NA.24

생물학적 소스

synthetic

Grade

pharmaceutical primary standard

Agency

EP

API family

dexamethasone

포장

pkg of 150 mg

제조업체/상표

EDQM

저장 조건

protect from light

색상

white

solubility

water: <0.1 g/L

응용 분야

pharmaceutical (small molecule)

형식

neat

배송 상태

ambient

저장 온도

2-8°C

SMILES string

[H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1(F)[C@@H](O)C[C@@]4(C)[C@@]2([H])C[C@@H](C)[C@]4(O)C(=O)COC(C)=O

InChI

1S/C24H31FO6/c1-13-9-18-17-6-5-15-10-16(27)7-8-21(15,3)23(17,25)19(28)11-22(18,4)24(13,30)20(29)12-31-14(2)26/h7-8,10,13,17-19,28,30H,5-6,9,11-12H2,1-4H3/t13-,17+,18+,19+,21+,22+,23+,24+/m1/s1

InChI key

AKUJBENLRBOFTD-RPRRAYFGSA-N

유전자 정보

human ... NR3C1(2908)

유사한 제품을 찾으십니까? 방문 제품 비교 안내

일반 설명

Dexamethasone acetate (Decadron-LA) belongs to the class of long-acting glucocorticoids, commonly used as a pharmaceutical ingredient in creams, ointments, microemulsions, lotions, aerosols, etc.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

애플리케이션

Dexamethasone acetate is used as an EP reference standard to quantify the analyte in pharmaceutical formulations using chromatography ttechniques.

포장

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

기타 정보

Sales restrictions may apply.

픽토그램

Health hazard

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Repr. 1B

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Dexamethasone acetate
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 10(3), 4963-4965 (2021)
Xuefan Xu et al.
Drug delivery, 18(7), 485-492 (2011-06-23)
This work studied the intravenous injection formulation of nanostructured lipid carriers (NLCs) loaded with dexamethasone acetate (DA), a poorly water-soluble drug. The goal of this study was to design nanoparticles which could improve therapeutic efficacy of DA on inflammations. Based
Kam-Lun Ellis Hon et al.
The Journal of dermatological treatment, 19(4), 241-245 (2008-07-17)
Many parents purchase topical applications without knowing what they contain, and apply them liberally to their children with dermatological disorders. In one such case, an infant developed fever, diarrhea and a small ulcer near the right labia majora which was
T Lifshitz et al.
Ophthalmic surgery and lasers, 32(2), 159-161 (2001-04-13)
Retrocorneal membranes after penetrating keratoplasty (PKP) is a well known complications, resulting from unintentional retention of the host Descemet's membrane (DM), or donor DM detachment. We describe for the first time the formation of a retrocorneal inflammatory membrane that mimics
Sandra A L Moura et al.
Journal of pharmaceutical sciences, 100(7), 2886-2895 (2011-02-02)
Implants are defined as controlled sustained release delivery systems of therapeutic agents incorporated or dispersed into a polymeric carrier. These systems can be implanted in specific organs and delivered by the therapeutic agents at the target site to treat various

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