SML1041

Atreleuton

≥98% (HPLC)

• 동의어(들): (R)-N-(3-(5-(4-Fluorophenylmethyl)thien-2-yl)-1-methyl-2-propynyl)-N-hydroxyurea, A8576, ABT 761, VIA-2291
• 실험식(Hill 표기법): C₁₆H₁₅FN₂O₂S
• CAS Number: 154355-76-7
• Molecular Weight: 318.37
• UNSPSC 코드: 51111800
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 광학 활성: [α]/D +40 to +50°, c = 1 in methanol
• 색상: white to beige
• solubility: DMSO: 10 mg/mL, clear
• 저장 온도: 2-8°C
• SMILES string: Fc1ccc(cc1)Cc2[s]c(cc2)C#C[C@H](N(O)C(=O)N)C
• InChI: 1S/C16H15FN2O2S/c1-11(19(21)16(18)20)2-7-14-8-9-15(22-14)10-12-3-5-13(17)6-4-12/h3-6,8-9,11,21H,10H2,1H3,(H2,18,20)/t11-/m1/s1
• InChI key: MMSNEKOTSJRTRI-LLVKDONJSA-N

설명

생화학적/생리학적 작용

Atreleuton is a reversible 5-lipoxygenase inhibitor.

Atreleuton is a reversible 5-lipoxygenase inhibitor. Atreleuton exhibits potent and selective inhibition of leukotriene formation both in vitro and in vivo.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302
• 예방조치 성명서: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable