추천 제품
Grade
certified reference material
pharmaceutical secondary standard
Quality Level
Agency
traceable to USP 1457403
API family
naproxen
CofA
current certificate can be downloaded
기술
HPLC: suitable
gas chromatography (GC): suitable
응용 분야
pharmaceutical (small molecule)
형식
neat
저장 온도
2-30°C
SMILES string
[Na+].COc1ccc2cc(ccc2c1)[C@H](C)C([O-])=O
InChI
1S/C14H14O3.Na/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10;/h3-9H,1-2H3,(H,15,16);/q;+1/p-1/t9-;/m0./s1
InChI key
CDBRNDSHEYLDJV-FVGYRXGTSA-M
유전자 정보
human ... PTGS1(5742) , PTGS2(5743)
유사한 제품을 찾으십니까? 방문 제품 비교 안내
일반 설명
Naproxen sodium (NS) is a sodium salt of propionic acid derivative and demonstrates analgesic, anti-pyretic, and anti-inflammatory properties. It exhibits efficiency in being used as an indomethacin in the treatment of acute musculoskeletal disorders. It belongs to the group of nonsteroidal anti-inflammatory drugs (NSAIDS) and acts by inhibiting the activity of both the cyclooxygenase enzymes, COX-1 & COX-2 and further blocking the synthesis of certain prostaglandins. It is administered in the treatment of ankylosing spondylitis, osteoarthritis, rheumatoid disorders, acute gout, mild to moderate pain, tendonitis, bursitis, dysmenorrhea, fever, and migraine headache. Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
애플리케이션
Naproxen sodium may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations and combined dosage forms by chromatographic and spectrophotometric techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
생화학적/생리학적 작용
Cyclooxygenase (Prostaglandin H synthase 1 and 2) inhibitor.
분석 메모
These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
기타 정보
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Values of analytes vary lot to lot.
각주
To see an example of a Certificate of Analysis for this material enter LRAA7178 in the slot below. This is an example certificate only and may not be the lot that you receive.
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 4 Oral - Repr. 1A
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
이미 열람한 고객
Effects of preoperative ibuprofen and naproxen sodium on orthodontic pain
The Angle Orthodontist, 75(5), 791-796 (2005)
Simultaneous determination of naproxen sodium and acetaminophen in fixed-dose combinations formulations by first-order derivative spectroscopy: application to dissolution studies
International Journal of Pharmacy and Pharmaceutical Sciences, 7(3), 183-188 (2015)
Rapid simultaneous determination of sumatriptan succinate and naproxen sodium in combined tablets by validated ultra performance liquid chromatographic method
Journal of Analytical and Bioanalytical Techniques , 2(3), 1-6 (2011)
Validated HPTLC method for simultaneous quantitation of domperidone maleate and naproxen sodium in bulk drug and formulation
Eurasian Journal of Analytical Chemistry, 5(3), 284-292 (2010)
Naproxen sodium, diflunisal, and placebo in the treatment of chronic back pain.
Annals of the Rheumatic Diseases, 41(2), 129-132 (1982)
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.