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Merck
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Key Documents

E9884

Sigma-Aldrich

Ethylenediaminetetraacetic acid

ACS reagent, 99.4-100.6%, powder

동의어(들):

(Ethylenedinitrilo)tetraacetic acid, EDTA, Edathamil, Ethylenedinitrilotetraacetic acid

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About This Item

Linear Formula:
(HO2CCH2)2NCH2CH2N(CH2CO2H)2
CAS Number:
Molecular Weight:
292.24
Beilstein:
1716295
EC Number:
MDL number:
UNSPSC 코드:
12352106
eCl@ss:
39030907
PubChem Substance ID:
NACRES:
NA.77

Quality Level

Grade

ACS reagent

Agency

suitable for SM 4500 - NH3

분석

99.4-100.6%

형태

powder

반응 적합성

reagent type: chelator

불순물

≤0.005% insoluble matter
≤0.1% Nitrilotriacetic acid ([HOCOCH2]3N)

무기 잔류물

≤0.2%

pH

2.5 (23 °C, 10 g/L)

mp

250 °C (dec.) (lit.)

solubility

water: soluble 0.4 g/L at 20 °C

양이온 미량물

Ca: ≤0.001%
Fe: ≤0.005%
Mg: ≤5 ppm
heavy metals: ≤0.001% (byICP-OES)

SMILES string

OC(=O)CN(CCN(CC(O)=O)CC(O)=O)CC(O)=O

InChI

1S/C10H16N2O8/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20)

InChI key

KCXVZYZYPLLWCC-UHFFFAOYSA-N

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일반 설명

Ethylenediaminetetraacetic acid (EDTA) is a hydrophilic metal chelating agent that transforms metal ions into inactive, cyclic metal complexes. Hence, it has industrial application for resolving metal contamination.

애플리케이션

Ethylenediaminetetraacetic acid has been used:
  • as a component of labeling buffer, which is used in the washing step during cell fractionation{155)
  • for investigating the effect of papain enzyme on wound debridement and other skin issues
  • for harvesting rat arterial smooth muscle cell after its pre-treatment for its use in flow cytometry analysis

생화학적/생리학적 작용

Ethylenediaminetetraacetic acid (EDTA) is not easily administered by the gastrointestinal tract. Intravenous administration of sodium EDTA results in hypocalcemic tetany. It is generally useful in plasma or molecular diagnostics and acts by chelating calcium. EDTA serves as an anticoagulant for haematological cell counting and cell morphological analysis.

추천 제품

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves


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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Henry's Clinical Diagnosis and Management by Laboratory Methods E-book, 28-28 (2011)
Streaming of proteolytic enzyme solutions for wound debridement: a feasibility study
Yaakobi T, et al.
Wounds : a compendium of clinical research and practice, 16, 201-205 (2004)
CRC Desk Reference of Clinical Pharmacology, 215-215 (1997)
Adsorption of metal-ethylenediaminetetraacetic acid chelates onto lake sediment
Sillanpaa M and Ramo J
Chemosphere, 45, 881-885 (2001)
Renée S Suen et al.
The American journal of pathology, 179(3), 1549-1559 (2011-07-02)
Because both endothelin-1 (ET-1) and angiotensin II (AngII) are independent mediators of arterial remodeling, we sought to determine the role of ET receptor inhibition in AngII-accelerated atherosclerosis and aortic aneurysm formation. We administered saline or AngII and/or bosentan, an endothelin

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