콘텐츠로 건너뛰기
Merck
모든 사진(1)

Key Documents

B-024

Supelco

Butabarbital solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

로그인조직 및 계약 가격 보기


About This Item

실험식(Hill 표기법):
C10H16N2O3
CAS Number:
Molecular Weight:
212.25
UNSPSC 코드:
41116107
PubChem Substance ID:
NACRES:
NA.24

Grade

certified reference material

형태

liquid

특징

SNAP-N-SPIKE®, SNAP-N-SHOOT®

포장

ampule of 1 mL

제조업체/상표

Cerilliant®

drug control

Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)

농도

1.0 mg/mL in methanol

기술

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

응용 분야

forensics and toxicology

형식

single component solution

저장 온도

−20°C

SMILES string

O=C(NC(C1(CC)C(C)CC)=O)NC1=O

InChI

1S/C10H16N2O3/c1-4-6(3)10(5-2)7(13)11-9(15)12-8(10)14/h6H,4-5H2,1-3H3,(H2,11,12,13,14,15)

InChI key

ZRIHAIZYIMGOAB-UHFFFAOYSA-N

일반 설명

Butabarbital is a barbiturate prescribed as a sleep aid under the trade name Butisol. sold under the name Butisol as a sleep aid. This analytical reference material is suitable for use in LC/MS or GC/MS applications for clinical toxicology, forensic analysis, or urine drug testing.

애플리케이션


  • Propranolol-D7 labeled solution: (±)-Propranolol-D₇ used in the analysis of β-blockers and metabolites in milk powder, employing high-performance liquid chromatography coupled to quadrupole Orbitrap high-resolution mass spectrometry. This application underscores the compound′s utility in sophisticated bioanalytical assessments, crucial for understanding pharmacokinetic behaviors in diverse matrices (Cheng et al., 2019).

  • Stable isotope-labeled propranolol for bioanalysis: Propranolol-D₇ used as an internal standard in a simultaneous determination method for propranolol and its metabolite in human plasma. The method, utilizing solid phase extraction and liquid chromatography/electrospray tandem mass spectrometry, highlights the role of stable isotopes in enhancing the precision and reliability of pharmacokinetic studies (Partani et al., 2009).

  • Propranolol-D₇ tracer for pharmacokinetic studies: (±)-Propranolol-D₇ employed in an innovative technique combining laser microdissection and liquid vortex capture-mass spectrometry for absolute quantitation of propranolol in thin tissue sections. This method allows for precise measurement of drug distribution in small, spatially distinct regions, enhancing the understanding of drug dynamics within organs (Cahill et al., 2016).


법적 정보

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

픽토그램

FlameSkull and crossbonesHealth hazard

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

표적 기관

Eyes

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point (°F)

49.5 °F - closed cup

Flash Point (°C)

9.7 °C - closed cup


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

T L Truman et al.
Pediatric emergency care, 10(4), 225-228 (1994-08-01)
A 16-month-old male presented with an overdose of Pyridium Plus--a combination anticholinergic, azo dye, and barbiturate--resulting in seizures, coma, and methemoglobinemia. This case report reviews the treatment of methemoglobinemia with methylene blue, activated charcoal, and exchange transfusion. Additionally, the role
Laurie A Zawertailo et al.
Journal of clinical psychopharmacology, 23(3), 269-280 (2003-06-27)
Implementation of regulations to control the prescribing of benzodiazepines in New York State in 1989 resulted in a 55% decrease in benzodiazepine prescribing, with a concomitant increase in the rates of prescribing older sedative-hypnotic compounds such as butabarbital (30% increase)
Elizabeth Loder
CNS drugs, 19(9), 769-784 (2005-09-07)
Fixed drug combinations (FDCs) combine standardised doses of two or more drugs in a single tablet, injection, nasal spray or suppository. FDCs may improve treatment compliance, efficacy or tolerability through a variety of mechanisms. At present, FDCs are commonly used
Y Martín-Biosca et al.
Journal of pharmaceutical and biomedical analysis, 21(2), 331-338 (2000-03-07)
A liquid chromatographic procedure for the determination of six barbiturates (barbital, diallyl barbituric acid, phenobarbital, butabarbital, amobarbital and pentobarbital) in urine samples is described. The proposed system uses a Spherisorb octadecyl-silane ODS-2 C18 analytical column and a guard column of

프로토콜

HPLC Analysis of Barbiturates in Serum on Discovery® C18 after SPE using Discovery® DSC-18Lt

자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..

고객지원팀으로 연락바랍니다.