D4007

5,5-Diphenylhydantoin

≥98%

• 동의어(들): 5,5-Diphenyl-2,4-imidazolidinedione, Phenytoin
• 실험식(Hill 표기법): C₁₅H₁₂N₂O₂
• CAS Number: 57-41-0
• Molecular Weight: 252.27
• Beilstein: 384532
• EC Number: 200-328-6
• MDL number: MFCD00005264
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24278370
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98%
• 양식: powder
• mp: 293-295 °C (lit.)
• solubility: DMSO: soluble
• SMILES string: O=C1NC(=O)C(N1)(c2ccccc2)c3ccccc3
• InChI: 1S/C15H12N2O2/c18-13-15(17-14(19)16-13,11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10H,(H2,16,17,18,19)
• InChI key: CXOFVDLJLONNDW-UHFFFAOYSA-N
• 유전자 정보: human ... CNR1(1268) , CNR2(1269) , CYP2C9(1559) , SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335) ; rat ... Faah(29347) , Scn1a(81574) , Scnn1g(24768) , Slc6a1(79212)

설명

일반 설명

5,5-Diphenylhydantoin is an anticonvulsant, which is used to treat tonic-clonic seizures, complex partial seizures and neurosurgical related seizures. It induces osteoblast proliferation and differentiation. 5,5-Diphenylhydantoin used to treat epilepsy. It reduces the hyperexcitability of tissues and may be associated with cerebellar atrophy.

애플리케이션

5,5-Diphenylhydantoin has been used for phenytoin treatment. It has also been used to slow down or prevent mesoendoderm cell migration.

생화학적/생리학적 작용

Reduces incidence of grand mal seizures; appears to stabilize excitable membranes perhaps through effects on Na⁺, K⁺, and Ca²⁺ channels.

안전성 정보

• 픽토그램: GHS08,GHS07
• 신호어: Danger
• 유해 및 위험 성명서: H302,H351,H360FD
• 예방조치 성명서: P202 - P264 - P280 - P301 + P312 - P308 + P313 - P405
• Hazard Classifications: Acute Tox. 4 Oral - Carc. 2 - Repr. 1B
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type P2 (EN 143) respirator cartridges