A78403

4-Aminopyridine

98%

• 동의어(들): 4-Pyridinamine, 4-Pyridylamine, 4AP, Fampridine
• 실험식(Hill 표기법): C₅H₆N₂
• CAS Number: 504-24-5
• Molecular Weight: 94.11
• Beilstein: 105782
• EC Number: 207-987-9
• MDL number: MFCD00006439
• UNSPSC 코드: 12352100
• PubChem Substance ID: 24891285
• NACRES: NA.22

속성

• Quality Level: 200
• 분석: 98%
• 양식: crystals
• bp: 273 °C (lit.)
• mp: 155-158 °C (lit.)
• solubility: H₂O: 50 mg/mL, clear, colorless
• SMILES string: Nc1ccncc1
• InChI: 1S/C5H6N2/c6-5-1-3-7-4-2-5/h1-4H,(H2,6,7)
• InChI key: NUKYPUAOHBNCPY-UHFFFAOYSA-N
• 유전자 정보: human ... KCNA1(3736) , KCNA10(3744) , KCNA2(3737) , KCNA3(3738) , KCNA4(3739) , KCNA5(3741) , KCNA6(3742) , KCNA7(3743) , KCNB1(3745) , KCNB2(9312) , KCNC1(3746) , KCNC2(3747) , KCNC3(3748) , KCNC4(3749) , KCND1(3750) , KCND2(3751) , KCND3(3752) , KCNF1(3754) , KCNG1(3755) , KCNG2(26251) , KCNG3(170850) , KCNG4(93107) , KCNH1(3756) , KCNH2(3757) , KCNH3(23416) , KCNH4(23415) , KCNH5(27133) , KCNH6(81033) , KCNH7(90134) , KCNH8(131096) , KCNQ1(3784) , KCNQ2(3785) , KCNQ3(3786) , KCNQ4(9132) , KCNQ5(56479) , KCNS1(3787) , KCNS2(3788) , KCNS3(3790) , KCNV1(27012) , KCNV2(169522) ; mouse ... Kcna3(16491) ; rat ... Grin2a(24409)

설명

일반 설명

4-aminopyridine is a ligand and an ion channel modulator used as an acetylcholine release enhancing agent.

애플리케이션

4-Aminopyridine (4-AP) can be used as a:

• Catalyst in the regioselective acylation of N-tosylhydrazide.
• Starting material in the synthesis of 4-aminopyridine derivatives for neurological disorder studies.
• Precursor for the synthesis of enantiomerically pure 4-(pyrrolidino)pyridine (PPY) derivatives by cyclocondensation reaction.

안전성 정보

• 픽토그램: GHS06,GHS05,GHS09
• 신호어: Danger
• 유해 및 위험 성명서: H300,H311 + H331,H314,H411
• 예방조치 성명서: P260 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 2 Oral - Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Aquatic Chronic 2 - Eye Dam. 1 - Skin Corr. 1B
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point (°F): 312.8 °F
• Flash Point (°C): 156 °C
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges