KCNQ3
potassium voltage-gated channel, KQT-like subfamily, member 3
Synonyms:
BFNC2, EBN2, KV7.3
Species:
Human KCNQ3 (3786), Mouse Kcnq3 (110862), Rat Kcnq3 (29682), Zebrafish kcnq3 (799747), cow KCNQ3 (281884), Horse KCNQ3 (100057886), domestic cat KCNQ3 (101093496), dog KCNQ3 (475103), chicken KCNQ3 (420325), domestic guinea pig Kcnq3 (100722068) ...More
UniProtKB ID:
Gene ID:
- Human(3786) Summary: The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and one of two related proteins encoded by the KCNQ2 and KCNQ5 genes, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 2 (BFNC2), also known as epilepsy, benign neonatal type 2 (EBN2). Two variants encoding distinct isoforms have been found. [provided by RefSeq, Mar 2011]
- Mouse(110862) potassium voltage-gated channel, subfamily Q, member 3
- Rat(29682) potassium voltage-gated channel, KQT-like subfamily, member 3
- Zebrafish(799747) potassium voltage-gated channel, KQT-like subfamily, member 3
- cow(281884) potassium voltage-gated channel, KQT-like subfamily, member 3
- Horse(100057886) potassium voltage-gated channel, KQT-like subfamily, member 3
- domestic cat(101093496) potassium voltage-gated channel, KQT-like subfamily, member 3
- dog(475103) potassium voltage-gated channel, KQT-like subfamily, member 3
- chicken(420325) potassium voltage-gated channel, KQT-like subfamily, member 3
- domestic guinea pig(100722068) potassium voltage-gated channel, KQT-like subfamily, member 3
- naked mole-rat(101726081) potassium voltage-gated channel, KQT-like subfamily, member 3
- sheep(101120673) potassium voltage-gated channel, KQT-like subfamily, member 3
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Small Molecule - Activator
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Description
Species
Antibodies
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Description
Species Reactivity
Application
Anti-KCNQ3 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot
Small Molecule - Blocker
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Description
Species
esiRNA
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Description
Species