KCNQ4
potassium voltage-gated channel, KQT-like subfamily, member 4
Synonyms:
DFNA2, DFNA2A, KV7.4
Species:
Human KCNQ4 (9132), Mouse Kcnq4 (60613), Rat Kcnq4 (298496), sheep KCNQ4 (101122655), Domestic Rabbit KCNQ4 (100358271), domestic guinea pig Kcnq4 (100716024), naked mole-rat Kcnq4 (101714294), chicken KCNQ4 (419643), domestic cat KCNQ4 (101091641), Horse KCNQ4 (100067963) ...More
UniProtKB ID:
Gene ID:
- Human(9132) Summary: The protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene. Defects in this gene are a cause of nonsyndromic sensorineural deafness type 2 (DFNA2), an autosomal dominant form of progressive hearing loss. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(60613) potassium voltage-gated channel, subfamily Q, member 4
- Rat(298496) potassium voltage-gated channel, KQT-like subfamily, member 4
- sheep(101122655) potassium voltage-gated channel, KQT-like subfamily, member 4
- Domestic Rabbit(100358271) potassium voltage-gated channel, KQT-like subfamily, member 4
- domestic guinea pig(100716024) potassium voltage-gated channel, KQT-like subfamily, member 4
- naked mole-rat(101714294) potassium voltage-gated channel, KQT-like subfamily, member 4
- chicken(419643) potassium voltage-gated channel, KQT-like subfamily, member 4
- domestic cat(101091641) potassium voltage-gated channel, KQT-like subfamily, member 4
- Horse(100067963) potassium voltage-gated channel, KQT-like subfamily, member 4
- cow(528741) potassium voltage-gated channel, KQT-like subfamily, member 4
- dog(482451) potassium voltage-gated channel, KQT-like subfamily, member 4
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Small Molecule - Activator
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-KCNQ4 antibody produced in mouse, clone 2H6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
mouse
Application
ELISA
western blot
western blot
Anti-KCNQ4 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Small Molecule - Blocker
Product Number
Description
Species
Small Molecule - Inhibitor
Product Number
Description
Species