902314

[CpRu(Fmoc-tyrosin)]CF₃CO₂

• 동의어(들): Fmoc-protected ruthenium tyrosine amino acid derivative, Peptide radiolabel precursor, [18F]Fluorophenylalanine peptide residue precursor
• 실험식(Hill 표기법): C₃₁H₂₆F₃NO₇Ru
• Molecular Weight: 682.61
• UNSPSC 코드: 12352209
• NACRES: NA.26

속성

• 양식: powder
• 반응 적합성: reaction type: Fmoc solid-phase peptide synthesis
• mp: >300 °C
• 응용 분야: peptide synthesis
• 작용기: Fmoc
• 저장 온도: 2-8°C
• SMILES string: O[C]1[CH][CH][C](CC(NC(OCC2C(C=CC=C3)=C3C4=C2C=CC=C4)=O)C(O)=O)[CH][CH]1.F[C-](F)F.O=C=O.[Ru+].c5cccc5

설명

애플리케이션

The Ritter lab has developed a new method for direct labeling of polypeptides with the [18F]fluoride radiolabel. This Fmoc-protected ruthenium tyrosine is first incorporated into peptides, which is amenable to standard solid-phase peptide synthesis (SPPS) and is tolerant of all 20 canonical amino acids. Subsequent replacement of a single hydrogen with fluorine-18, with only minimal perturbation of the peptide structure, results in a site-specific, radiolabeled peptide tracer for use with positron emission tomography (PET) imaging in the study of various biological applications.

주의사항

Research quantities limited to 10 g.

기타 정보

Site-SpecificDeoxyfluorination of Small Peptides with [18F]Fluoride

법적 정보

Patent Application EP18204755.5
This product is manufactured pursuant to a license with Studiengesellschaft Kohle mbH

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable