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Merck
모든 사진(1)

주요 문서

906794

Bis(neopentyltrimethylammonium) oxalate

동의어(들):

N,N,N,2,2-Pentamethylpropan-1-aminium oxalate, Bis(trimethylneopentylammonium) oxalate

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About This Item

실험식(Hill 표기법):
C18H40N2O4
CAS Number:
Molecular Weight:
348.52

양식

powder, crystals or chunks

저장 온도

−20°C

애플리케이션

This bis(neopentyltrimethylammonium) oxalate is used in the elution step of the Ritter lab′s new method for deoxyfluorination of phenols. First, an Fmoc-protected ruthenium tyrosine amino acid derivative ([CpRu(Fmoc-tyrosin)]CF3CO2, cat# 902314) is incorporated to a peptide. Later, bis(neopentyltrimethylammonium) oxalate and chloroimidazolium chloride (cat# 904848) facilitate the elution of [18F]fluoride. The final [18F]fluoride radiolabeled polypeptide is useful in positron emission tomography (PET) imaging for the study of various biological applications.

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주의사항

Bis(neopentyltrimethylammonium) oxalate is hygroscopic and should be stored in a closed vial or in a desiccator.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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시험 성적서(COA)

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문서 라이브러리 방문

Jens Rickmeier et al.
Angewandte Chemie (International ed. in English), 57(43), 14207-14211 (2018-09-07)
Radiolabeled receptor-binding peptides are an important class of positron emission tomography tracers owing to achievable high binding affinities and their rapid blood clearance. Herein, a method to introduce a 4-[18 F]fluoro-phenylalanine residue into peptide sequences is reported, by chemoselective radio-deoxyfluorination

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