420069

4,5-Dimethoxy-2-nitrobenzyl chloroformate

97%, for peptide synthesis

• 동의어(들): 6-Nitroveratryl chloroformate, 6-Nitroveratryloxycarbonyl chloride, NVOC chloride, NVOC-Cl
• Linear Formula: ClCO₂CH₂C₆H₂(OCH₃)₂NO₂
• CAS Number: 42855-00-5
• Molecular Weight: 275.64
• Beilstein: 2389168
• MDL number: MFCD00143507
• UNSPSC 코드: 12352101
• PubChem Substance ID: 24866307
• NACRES: NA.22

속성

• 제품명: 4,5-Dimethoxy-2-nitrobenzyl chloroformate, 97%
• Quality Level: 200
• 분석: 97%
• 양식: powder
• mp: 125 °C (dec.) (lit.)
• 응용 분야: peptide synthesis
• 작용기: chloro; nitro
• 저장 온도: 2-8°C
• SMILES string: COc1cc(COC(Cl)=O)c(cc1OC)[N+]([O-])=O
• InChI: 1S/C10H10ClNO6/c1-16-8-3-6(5-18-10(11)13)7(12(14)15)4-9(8)17-2/h3-4H,5H2,1-2H3
• InChI key: RWWPKIOWBQFXEE-UHFFFAOYSA-N

설명

애플리케이션

4,5-Dimethoxy-2-nitrobenzyl chloroformate (NVOC-Cl) is a photolabile protecting reagent, commonly used in peptide or nucleotide synthesis to protect amines and hydroxyl groups. General applications are:

• Preparation of inactive, caged protein conjugates which can be activated by irradiating near-ultraviolet light.
• Solid-phase synthesis of base-sensitive S-acylthioethyl (SATE)-prooligonucleotides.
• Modification of surface properties by introducing photocleavable NVOC moiety into chitosan to control cell attachment.

안전성 정보

• 픽토그램: GHS05
• 신호어: Danger
• 유해 및 위험 성명서: H314
• 예방조치 성명서: P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363
• Hazard Classifications: Skin Corr. 1B
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges