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Merck

LC/MS Analysis of CYP2D6 Inhibitors on Ascentis® Express HILIC

LC/MS Analysis of CYP2D6 Inhibitors on Ascentis® Express HILIC application for HPLC

材料

Standard

製品番号
詳細
価格

I7379

イミプラミン 塩酸塩

≥99% (TLC)

1500218

パロキセチン 塩酸塩

United States Pharmacopeia (USP) Reference Standard

PHR1384

アミトリプチリン 塩酸塩

Pharmaceutical Secondary Standard; Certified Reference Material

PHR1394

フルオキセチン 塩酸塩

Pharmaceutical Secondary Standard; Certified Reference Material

分析カラム

製品番号
詳細
価格

53939-U

Ascentis® Express HILIC、2.7 μm HPLCカラム

2.7 μm particle size, L × I.D. 10 cm × 2.1 mm

移動相成分

製品番号
詳細
価格

70221

ギ酸アンモニウム

eluent additive for LC-MS, LiChropur™, ≥99.0%

CONDITIONS

column

Ascentis Express HILlC, 10 cm x 2.1 mm I.D., 2.7 μm particles (53939-U)

mobile phase

5 mM ammonium formate in 2:98 (v/v) water:acetonitrile

flow rate

1.2 mL/min

column temp.

50 °C

detector

ESI(+), m/z 100-400

injection

0.5 μL

詳細

アナリシスノート

This application demonstrates the suitability of the Ascentis Express HILIC for the analysis of CYP2D6 Inhibitors.

法的情報

Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany

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