V3388

血管内皮増殖因子 (aa 207-318) ヒト

≥97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder

• 別名: _VEGF}112, VEGF₁₂₁, バスキュロトロピン
• MDL番号: MFCD00286542
• UNSPSCコード: 12352202
• NACRES: NA.32

特性

• product name: 血管内皮増殖因子 (aa 207-318) ヒト, ≥97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder
• 由来生物: human
• 品質水準: 100
• リコンビナント: expressed in E. coli
• アッセイ: ≥97% (SDS-PAGE)
• 形状: lyophilized powder
• 有効性: 0.75-3.75 ng/mL ED₅₀
• 分子量: predicted mol wt ~28 kDa
• 包装: pkg of 5 μg
• 保管条件: avoid repeated freeze/thaw cycles
• 不純物: <1 EU/μg
• UniProtアクセッション番号: P15692
• 保管温度: −20°C
• 遺伝子情報: human ... VEGFA(7422)

詳細

アプリケーション

Vascular Endothelial Growth Factor (aa 207-318) human also known as VEGF 121 was used for preparing a cellular matrix hybridized with hyaluronic acid (ACM-HA) VEGF constructs which is used in measuring the VEGF-enhanced tissue-engineered bladder graft neovascularization by using dynamic contrast-enhanced MRI. The product was used for creating VEGF-impregnated tissue-engineered construct which was inserted in the critical-sized calvarial defect in the membranous parietal bone of the rabbit for examining and characterizing the angiogenesis necessary for bone formation.

生物化学的／生理学的作用

Vascular Endothelial Growth Factor (aa 207-318) human also referred to as VEGF 121 or Vasculotropin is a basic protein that induces endothelial cell growth, vasculogenesis and angiogenesis. VEGF also enhances the growth of endothelial cells isolated from cerebral cortex, fetal and adult aorta as well as human umbilical vein. Cells enhance VEGF 121 secretion from fibrin implants results in local and controlled blood vessel growth.

in vivoでの強力な血管形成誘導因子です。

その他情報

ヒトVEGFの112アミノ酸残基バリアント。

物理的形状

凍結乾燥品(30%アセトニトリル、0.1% TFA溶液、0.25mg BSA含有、0.2μmフィルター滅菌済み)。

アナリシスノート

生物活性は、ヒト臍静脈内皮細胞の³H-チミジン取り込みの刺激能により測定しています。

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, type N95 (US)