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安全性情報

T2402

Sigma-Aldrich

抗マウスIgG抗体(全分子)抗体–TRITC標識 ウサギ宿主抗体

IgG fraction of antiserum, buffered aqueous solution

別名:

Rabbit Anti-Mouse IgG (whole molecule)−Tetramethylrhodamine isothiocyanate

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About This Item

MDL番号:
UNSPSCコード:
12352203
NACRES:
NA.46

由来生物

rabbit

品質水準

結合体

TRITC conjugate

抗体製品の状態

IgG fraction of antiserum

抗体製品タイプ

secondary antibodies

クローン

polyclonal

フォーム

buffered aqueous solution

保管条件

protect from light

テクニック

direct immunofluorescence: 1:64
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:200

保管温度

−20°C

ターゲットの翻訳後修飾

unmodified

詳細

Immunoglobulins (Igs) belongs immunoglobulin super-family. There are five different types of Immunoglobulins. Each immunoglobulin has two heavy (H) and two light (L), held together by disulphide linkages. Each light comprises one variable N-terminal region and a constant C-terminal region. Heavy chain has one variable N-terminal region and three or four constant (CH1-CH4) C-terminal region. IgG is abundant immunoglobulin in human serum. The four classes of IgG can be IgG1, IgG2, IgG3, and IgG4.

特異性

Anti-Mouse IgG (whole molecule)-TRITC antibody is specific for mouse IgG.

免疫原

Normal mouse serum

アプリケーション

Anti-Mouse IgG (whole molecule)-TRITC antibody is suitable for use in direct immunofluorescence (1:64), immunohistochemistry (1:200 dilution in formalin-fixed, paraffin-embedded sections), Ouchterlony double diffusion and electrophoresis techniques.

生物化学的/生理学的作用

Digestion of IgG by papain results in generation of fragment antigen binding (Fab) comprising one complete L chain and a variable and CH1 region of H chain. Pepsin digestion of IgG results in fragment crystallizable (fc), comprises the H chain constant region.
Immunoglobulin G (IgG) is a glycoprotein antibody that regulates immune responses such as phagocytosis and is also involved in the development of autoimmune diseases . Mouse IgGs have four distinct isotypes, namely, IgG1, IgG2a, IgG2b, and IgG3. IgG1 regulates complement fixation in mice .

物理的形状

0.01M PBS溶液 (pH 7.4, 15mMアジ化ナトリウム含有)。

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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保管分類コード

10 - Combustible liquids

WGK

nwg

引火点(°F)

Not applicable

引火点(℃)

Not applicable

個人用保護具 (PPE)

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

T2402-VAR:
IXO31221:
T2402-2ML:
T2402-BULK:


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文書ライブラリにアクセスする

Mikkel Wölck Misfeldt et al.
Investigative ophthalmology & visual science, 51(12), 6681-6687 (2010-08-07)
The retinal blood flow is regulated by the tone of resistance arterioles, which is influenced by purinergic compounds such as adenosine and adenosine 5'-triphosphate (ATP) released from the retinal tissue. However, it is unknown what cellular elements in the perivascular
Rajbir K Gill et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 14(22), 7481-7487 (2008-11-18)
We seek to establish a genetic test to identify lung cancer using cells obtained through computed tomography-guided fine needle aspiration (FNA). We selected regions of frequent copy number gains in chromosomes 1q32, 3q26, 5p15, and 8q24 in non-small cell lung
Kathryn S Poland et al.
Genes, chromosomes & cancer, 46(9), 805-812 (2007-06-01)
Studying the molecular basis of familial renal cell carcinoma (RCC) has allowed identification of novel RCC genes involved in the pathogenesis of both inherited and sporadic RCC. We describe a constitutional balanced t(3;8)(p14;q24.1) translocation found in a brother and sister
Jessica E Poort et al.
Human molecular genetics, 25(17), 3768-3783 (2016-08-06)
Spinal bulbar muscular atrophy (SBMA) is a progressive, late onset neuromuscular disease causing motor dysfunction in men. While the morphology of the neuromuscular junction (NMJ) is typically affected by neuromuscular disease, whether NMJs in SBMA are similarly affected by disease
Su-Jin Heo et al.
eLife, 5 (2016-12-03)
Mesenchymal stem cell (MSC) differentiation is mediated by soluble and physical cues. In this study, we investigated differentiation-induced transformations in MSC cellular and nuclear biophysical properties and queried their role in mechanosensation. Our data show that nuclei in differentiated bovine

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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