SRP8044

CD40L, Soluble human

recombinant, expressed in CHO cells, FLAG^® tagged, >95% (SDS-PAGE)

• 別名: ACRP30headless:CD154, ACRP30headless:CD40L, ACRP30headless:TNFSF5, ADIPOQ-CD40L
• UNSPSCコード: 12352200
• NACRES: NA.77

特性

• 由来生物: human
• リコンビナント: expressed in CHO cells
• タグ: FLAG^® tagged
• アッセイ: >95% (SDS-PAGE)
• 形状: lyophilized
• 分子量: 35-40 kDa by SDS-PAGE
• 包装: pkg of 10 μg
• 保管条件: avoid repeated freeze/thaw cycles
• 不純物: <0.01 EU/μg endotoxin, tested
• UniProtアクセッション番号: P29965
• 輸送温度: wet ice
• 保管温度: −20°C
• 遺伝子情報: human ... CD40LG(959)

詳細

詳細

CD40L (cluster of differentiation 40 ligand) belongs to the tumor necrosis factor (TNF) family, and is expressed by basophils, B cells, monocytic cells, natural killer cells, platelets, mast cells and T cells. It is predominantly expressed on pro-inflammatory T cells. It also exists in a soluble form.

生物化学的／生理学的作用

CD40L (cluster of differentiation 40 ligand) is active in its membrane-bound form. It interacts with CD40 and functions as a proinflammatory and procoagulant agent. The serum levels of soluble CD40L is elevated in malignant middle cerebral artery infarction (MMCAI) patients, especially in non-surviving patients.

物理的形状

凍結乾燥品(炭酸アンモニウム)。

再構成

Reconstitute with 100 μL deionized water.

その他情報

Human CD40L (aa 116-261) is fused at the N-terminus to mouse ACRP30headless (aa 18-111) and a FLAG^®-tag.

法的情報

FLAG is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable