SRP6057

アクチビンA マウス由来

recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC)

• 別名: FRP, インヒビンβ-1
• UNSPSCコード: 12352202
• NACRES: NA.32

特性

• 由来生物: mouse
• リコンビナント: expressed in E. coli
• アッセイ: ≥95% (HPLC); ≥95% (SDS-PAGE)
• フォーム: lyophilized
• 分子量: 26.2 kDa
• 包装: pkg of 10 μg
• テクニック: cell culture | embryo: suitable
• NCBIアクセッション番号: P08476
• 輸送温度: wet ice
• 保管温度: −20°C
• 遺伝子情報: mouse ... INHBA(3624)

詳細

詳細

Activin A is a member of the TGF (transforming growth factor)-β family of proteins produced by many cell types throughout development. Mouse Activin A has 100% amino acid sequence identity to human, rat, porcine, bovine and feline proteins. Recombinant mouse Activin A is a nonglycosylated homodimer, containing two 117 amino acid chains, with a total molecular weight of 26.2 kDa.

アプリケーション

Activin A has been used:

• to induce differentiation of embryonic stem cells to pancreatic β cells
• in the induction of bone marrow-derived mesenchymal stem cells to insulin-producing cells
• to induce endoderm differentiation from human embryonic stem cells
• as a component of β cell induction medium.

生物化学的／生理学的作用

Activins interact with Type I and Type II serine/threonine kinases to signal to SMAD proteins to regulate a variety of functions, including cell proliferation, differentiation, wound healing, apoptosis, metabolism, etc. Activin A is a homodimer of two β A chains and is not biologically active until the N terminal propeptide is cleaved from each chain. Activin A is involved in mesoderm formation and hematopoietic development.

物理的形状

Recombinant mouse Activin A is lyophilized with 0.02% TFA.

調製ノート

バイアルは、開封前に遠心してください。

再構成

Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water, which can then be further diluted to other aqueous solutions.

その他情報

MGLECDGKVN ICCKKQFFVS FKDIGWNDWI IAPSGYHANY CEGECPSHIA GTSGSSLSFH STVINHYRMR GHSPFANLKS CCVPTKLRPM SMLYYDDGQN IIKKDIQNMI VEECGCS

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H315,H319
• 注意書き: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• 危険有害性の分類: Eye Irrit. 2 - Skin Irrit. 2
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable