SML3387

Rilpivirine

≥98% (HPLC)

• 別名: 4-[[4-[[4-[(1E)-2-Cyanoethenyl]-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile, R 278474, TMC 278
• 実験式（ヒル表記法）: C₂₂H₁₈N₆
• CAS番号: 500287-72-9
• 分子量: 366.42
• MDL番号: MFCD11046372
• UNSPSCコード: 51111800
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• 形状: powder
• 色: white to beige
• 溶解性: DMSO: 2 mg/mL, clear
• 保管温度: 2-8°C
• SMILES記法: CC1=CC(=CC(=C1NC2=NC(=NC=C2)NC3=CC=C(C=C3)C#N)C)/C=C/C#N
• InChI: 1S/C22H18N6/c1-15-12-18(4-3-10-23)13-16(2)21(15)27-20-9-11-25-22(28-20)26-19-7-5-17(14-24)6-8-19/h3-9,11-13H,1-2H3,(H2,25,26,27,28)/b4-3+
• InChI Key: YIBOMRUWOWDFLG-ONEGZZNKSA-N

詳細

生物化学的／生理学的作用

Rilpivirine is a next generation nonnucleoside reverse transcriptase inhibitor (NNRTI), It has been shown to be active against many HIV strains with mutations that confer resistance to the first-generation NNRTIs.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable